2,324 Result(s)
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Han**g Wang
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Article
Development of a loop-mediated isothermal amplification assay for rapid and sensitive detection of Hemileia vastatrix in coffee plantations
Coffee leaf rust (CLR) caused by Hemileia vastatrix is a devastating worldwide disease. Early monitoring is crucial for controlling CLR quickly and efficiently. However, accurately identifying CLR in its early st...
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Open AccessPig blastocyst-like structure models from embryonic stem cells
Pluripotent stem cells have the potential to generate embryo models that can recapitulate developmental processes in vitro. Large animals such as pigs may also benefit from stem-cell-based embryo models for im...
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Open AccessManagement and treatment of severe immune-related hepatotoxicity based on clinical and pathological characteristics
The management of severe immune-related hepatotoxicity (irH) needs to be further optimized. This study aims to analyze the clinical characteristics of severe irH; improve the therapeutic strategy, especially s...
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Open AccessEffect of esketamine combined with dexmedetomidine on delirium in sedation for mechanically ventilated ICU patients: protocol for a nested substudy within a randomized controlled trial
Use of sedatives and analgesics is associated with the occurrence of delirium in critically ill patients receiving mechanical ventilation. Dexmedetomidine reduces the occurrence of delirium but may cause hypot...
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Open AccessA novel variant in GAS2 is associated with autosomal dominant nonsyndromic hearing impairment in a Chinese family
Knockout of GAS2 (growth arrest-specific protein 2), causes disorganization and destabilization of microtubule bundles in supporting cells of the cochlear duct, leading to hearing loss in vivo. However, the molec...
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Animal Models of Chronic Migraine: From the Bench to Therapy
Chronic migraine is a disabling progressive disorder without effective management approaches. Animal models have been developed and used in chronic migraine research. However, there are several problems with e...
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Integrative analyses of transcriptome, microRNA-seq and metabolome reveal insights into exogenous melatonin-mediated salt tolerance during seed germination of maize
Melatonin is an important phytohormone influencing plant growth and defense responses. However, the mechanism mediating the regulatory effects of melatonin on the salt tolerance of germinating maize seeds rema...
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Open AccessAn increase of serum CA-125 to two times of nadir level strongly predicts the image-identified relapse of serous ovarian cancer
Using 70 U/ml or 35 U/ml as CA125 routine abnormal threshold may result in omissions in the relapse detection of Ovarian cancer (OvCa). This study aimed to clarify the association between a biochemical relapse...
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Exploring the Association Between Bullying Victimization and Poor Mental Health in Rural Chinese Adolescents: The Mediating Effects of Emotion Regulation
Bullying is one of the most common forms of school violence. Although the negative impact of bullying victimization on students’ mental health outcomes has been well documented, the underlying mechanism of the...
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Open AccessBiological characteristics and metabolic phenotypes of different anastomosis groups of Rhizoctonia solani strains
Rhizoctonia solani is an important plant pathogen worldwide, and causes serious tobacco target spot in tobacco in the last five years. This research studied the biological characteristics of four different anasto...
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A machine-learning-based peridynamic surrogate model for characterizing deformation and failure of materials and structures
It is necessary to determine the input features and output results when constructing a surrogate model within the data-driven neural network. Since the law of features would be restrained when the surrogate me...
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Control of the nonlinear flutter of a rectangular cylinder using auxiliary flexible films
Wind tunnel experiments were conducted to test the effects of auxiliary flexible films (FFs) attached at the leading edges of a rectangular cylinder on its nonlinear flutter. The aspect ratio (B/D) of the tested ...
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Synergistic rare-earth yttrium single atoms and copper phosphide nanoparticles for high-selectivity ammonia electrosynthesis
Electrochemical nitrate reduction to NH3 holds a great promise for N-upcycling in nature, while its sluggish reaction kinetics involved in both the stepwise deoxygenation and hydrogenation processes necessitates ...
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Deep learning based insulator fault detection algorithm for power transmission lines
Aiming at the complex background of transmission lines at the present stage, which leads to the problem of low accuracy of insulator fault detection for small targets, a deep learning-based insulator fault det...
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Open AccessDevelopment and validation of a risk prediction model for invasiveness of pure ground-glass nodules based on a systematic review and meta-analysis
Assessing the aggressiveness of pure ground glass nodules early on significantly aids in making informed clinical decisions.
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Open AccessIncidence and treatment-related risk factors of inhibitor development after intensive FVIII replacement for major orthopaedic surgery in previous treated haemophilia A
Haemophilia A (HA) is an X-linked recessive bleeding disorder caused by lack or deficiency of coagulation factor VIII.
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Validating the use of ROS-scavenging bacteria as probiotics to increase coral resilience to thermal stress
Thermal stress causes the overproduction and toxic accumulation of reactive oxygen species (ROS), which seems to be correlated with coral bleaching and, ultimately, death. The reduction of ROS concentration wi...
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Discrimination and simultaneous quantification of poly(ethylene terephthalate) and poly(butylene terephthalate) microplastics in environmental samples via gas chromatography-tandem mass spectrometry
A method has been developed to quantify PET and PBT microplastics (MPs) based on depolymerization and detection of depolymerization products by gas chromatography-tandem mass spectrometry (GC–MS/MS) without a...
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Open AccessA Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex
This study aimed to identify possible pathogenic genes in a 90-member family with a rare combination of multiple neurodegenerative disease phenotypes, which has not been depicted by the known neurodegenerative...
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Open AccessHNRNPA2B1 stabilizes NFATC3 levels to potentiate its combined actions with FOSL1 to mediate vasculogenic mimicry in GBM cells
Vasculogenic mimicry (VM) is an enigmatic physiological feature that influences blood supply within glioblastoma (GBM) tumors for their sustained growth. Previous studies identify NFATC3, FOSL1 and HNRNPA2B1 a...
