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  1. Article

    Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons

    Members of the NR1I subfamily of nuclear receptors play a role in the transcriptional activation of genes involved in drug metabolism and transport. NR1I3, the constitutive androstane receptor (CAR), mediates ...

    Emma E Thompson, Hala Kuttab-Boulos, Matthew D Krasowski, Anna Di Rienzo in Human Genomics (2005)