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    Defective cleavage of membrane bound TGFα leads to enhanced activation of the EGF receptor in malignant cells

    Transforming growth factor α (TGFα) is widely expressed in malignant as well as normal cells and is involved in regulating cell growth and differentiation. Although processing of TGFα has been extensively stud...

    Haisu Yang, Dianhua Jiang, Wenhui Li, Jiurong Liang, Larry E Gentry… in Oncogene (2000)