-
Chapter
The Restructuring of the Chinese Automotive Industry: the Role of Foreign Direct Investment and the Impact of European Multinational Enterprises
This chapter studies the restructuring of the Chinese automotive industry since the 1980s and the impact of FDI on this ongoing process. The main focus is the evaluation of the role of European MNEs in the dev...
-
Article
A hierarchical framework for visualising and simulating supply chains in virtual environments
This paper presents research into applying virtual environment (VE) technology to supply chain management (SCM). Our research work has employed virtual manufacturing environments to represent supply chain node...
-
Chapter and Conference Paper
Simulation Line Design Using BP Neural Network
The simulation line is usually used to imitate the frequency characteristic of a real long transmission line. This paper proposes a novel design scheme of simulation line using back propagation neural network ...
-
Article
Dynamics of the colloidal suspensions
This article offers a survey on our current knowledge of the dynamics of the colloidal suspension, where each particle experiences the friction force with solvent, hydrodynamic interaction, and potential force...
-
Article
Open AccessAntisurvivin oligonucleotides inhibit growth and induce apoptosis in human medullary thyroid carcinoma cells
Suvivin is a novel member of the inhibitor of apoptosis protein (IAP) family, which is known to be over-expressed in various carcinomas and associated with their biologically aggressive characteristics. The ai...
-
Article
Improvement of chronic heart failure by dexamethasone is not associated with downregulation of leptin in rats
To demonstrate the hypothesis that dexamethasone (Dex) could improve chronic heart failure (CHF) by inhibiting the downstream signaling transduction of leptin but had no influence on the upregulation of leptin...
-
Article
Studies of Natural Products on Treating Neurological Disorders in China
-
Article
Non-cholinergic Effects of Huperzine A: Beyond Inhibition of Acetylcholinesterase
The use of acetylcholinesterase inhibitors to decrease the breakdown of the neurotransmitter acetylcholine has been the main symptomatic therapy for mild to moderate Alzheimer’s patients, though the etiology ...
-
Article
Synthesis, Crystal Structure, and Properties of [Dy(p-ABA)3Phen · H2O] · 1.5H2O1
(1.10-Phenanthroline)-tris(4-amidobenzoate)dysprosium, [Dy(p-ABA)3Phen · H2O] · 1.5H2O (where p-ABA = p-amidobenzoate and Phen = 1.10-phenanthroline) has been synthesized. The complex was characterized by element...
-
Chapter and Conference Paper
A Precise Method for Detecting Harmonics in Electric Power System Based on Wavelet Package Transform
At present the precise harmonics detection of the power system has great significance for the security of the power system. In this paper, the application of the wavelet package transform in the detection of t...
-
Article
Discovery of potent β-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids
The aim of this study was to design and synthesize a series of high activity compounds against aspartyl protease β-secretase (BACE-1) bearing hydroxyethylene (HE) framework.
-
Article
Open AccessRole of oxidative stress and intracellular glutathione in the sensitivity to apoptosis induced by proteasome inhibitor in thyroid cancer cells
The proteasome inhibitor bortezomib has shown impressive clinical activity alone and in combination with conventional and other novel agents for the treatment of multiple myeloma (MM) and some solid cancers. A...
-
Article
Open AccessTunicamycin enhances TRAIL-induced apoptosis by inhibition of cyclin D1 and the subsequent downregulation of survivin
TNF-related apoptosis-inducing ligand (TRAIL) has been proposed as a promising cancer therapy that preferentially induces apoptosis in cancer cells, but not most normal tissues. However, many cancers are resis...
-
Article
Cholinergic deficiency involved in vascular dementia: possible mechanism and strategy of treatment
Vascular dementia (VaD) is a progressive neurodegenerative disease with a high prevalence. Several studies have recently reported that VaD patients present cholinergic deficits in the brain and cerebrospinal f...
-
Article
Novel 16-substituted bifunctional derivatives of huperzine B: multifunctional cholinesterase inhibitors
To design novel bifunctional derivatives of huperzine B (HupB) based on the concept of dual binding site of acetylcholinesterase (AChE) and evaluate their pharmacological activities for seeking new drug candid...
-
Article
Significance of survivin, caspase-3, and VEGF expression in thyroid carcinoma
To investigate the clinical significance of survivin, caspase-3, and vascular endothelial growth factor expression in a subset of thyroid carcinoma and their correlation with prognosis. Sixty-eight cases of th...
-
Article
Synthesis and crystal structure of the complex [Sm(p-MOBA)3bipy]2 · 2C2H5OH
A new binuclear complex [Sm(p-MOBA)3bipy]2 · 2C2H5OH (p-MOBA = p-methoxybenzoate, bipy = 2,2′-bipyridine) has been prepared via dissolution reaction in an ethanol/water mixed solution and characterized by element...
-
Article
Retrospect and prospect of active principles from Chinese herbs in the treatment of dementia
With an ageing population, dementia has become one of the world's primary health challenges. However, existing remedies offer limited benefits with certain side effects, which has prompted researchers to seek ...
-
Article
Effect of interrupted endogenous BMP/Smad signaling on growth and steroidogenesis of porcine granulosa cells
Bone morphogenetic proteins (BMPs) play a critical role in the growth and steroidogenesis of granulosa cells (GCs). BMP signals act through membrane-bound heteromeric serine/threonine kinase receptors. Upon li...
-
Chapter and Conference Paper
A Process Positioning System for Sheet-Fed Offset Press
Sheet positioning time is one of the main influence factors to improve the printing velocity of offset printing press. In the process positioning system, step** motor, transducer and roller wheels replace th...
