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Article
Effective length factor of a non-symmetrical cross-bracing system with a discontinuous diagonal
A non-rectangular frame panel usually contains an asymmetrical cross-bracing system with interrupted diagonals, leading to a more complicated buckling behavior than a symmetrical bracing system with continuous...
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Article
Open AccessHuman embryonic stem cell-derived retinal pigment epithelium transplants as a potential treatment for wet age-related macular degeneration
Stem cell therapy may provide a safe and promising treatment for retinal diseases. Wet age-related macular degeneration (wet-AMD) is a leading cause of blindness in China. We developed a clinical-grade human e...
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Article
Open AccessLong-term safety of human retinal progenitor cell transplantation in retinitis pigmentosa patients
Retinitis pigmentosa is a common genetic disease that causes retinal degeneration and blindness for which there is currently no curable treatment available. Vision preservation was observed in retinitis pigmen...
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Article
Oridonin suppress cell migration via regulation of nonmuscle myosin IIA
Oridonin, which is isolated from Chinese herb Rabdosia rubescens (Hemsl.) Hara, has been implicated in regulation of tumor cell migration and invasion. In this study, treatment with oridonin enhanced the phosphor...
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Article
Detecting novel genetic mutations in Chinese Usher syndrome families using next-generation sequencing technology
Usher syndrome (USH) is the most common cause of combined blindness and deafness inherited in an autosomal recessive mode. Molecular diagnosis is of great significance in revealing the molecular pathogenesis a...
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Article
Effect of Optogenetic Stimulus on the Proliferation and Cell Cycle Progression of Neural Stem Cells
Modulation of stem cell proliferation is a crucial aspect of neural developmental biology and regenerative medicine. To investigate the effect of optical stimulation on neural stem cell proliferation, cells tr...
