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  1. Article

    Inhibition of human pancreatic cancer growth in nude mice by boron neutron capture therapy

    Immunoliposomes were prepared by conjugating anti-carcinoembryonic antigen (CEA) monoclonal antibody with liposomes containing [10B]compound. These immunoliposomes were shown to bind selectively to human pancr...

    H Yanagië, T Tomita, H Kobayashi, Y Fujii, Y Nonaka, Y Saegusa in British Journal of Cancer (1997)

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    Article

    A targeting model of boron neutron-capture therapy to hepatoma cellsin vivo with a boronated anti-(α-fetoprotein) monoclonal antibody

    We described previously that10B atoms delivered by monoclonal antibody (mAb) exerted a cytotoxic effect on AH66 cells in a dose-dependent manner upon thermal neutron irradiationin vitro. In the present study, the...

    H. Yanagië, Y. Fujii, M. Sekiguchi in Journal of Cancer Research and Clinical On… (1994)

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    Article

    Application of boronated anti-CEA immunoliposome to tumour cell growth inhibition in in vitro boron neutron capture therapy model

    An immunoliposome containing a 10B-compound has been examined as a selective drug delivery system in boron neutron-capture therapy. Liposomes, conjugated with monoclonal antibodies specific for carcinoembryoni...

    H Yanagië, T Tomita, H Kobayashi, Y Fujii, T Takahashi in British Journal of Cancer (1991)