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Article
Optimization in a Nonlinear Lanchester-Type Model Involving Supply Units \(^* \)
In this paper, we introduce a nonlinear Lanchester-type model involving supply units. The model describes a battle where the Blue party consisting of one armed force
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Article
Automatic crack detection from 2D images using a crack measure-based B-spline level set model
A method is proposed for automatic detection of cracks extracted from 2D images of damaged structures. In the 2D images, the cracks are treated as tree-like topological dark objects of which each tree branch i...
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Article
Open AccessCharacterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization
PTEN is a PIP3 phosphatase that antagonizes oncogenic PI3-kinase signalling. Due to its critical role in suppressing the potent signalling pathway, it is one of the most mutated tumour suppressors, especially ...
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Article
A new class of cancer-associated PTEN mutations defined by membrane translocation defects
Phosphatase and tensin homolog (PTEN), which negatively regulates tumorigenic phosphatidylinositol (3,4,5)-trisphosphate (PIP3) signaling, is a commonly mutated tumor suppressor. The majority of cancer-associa...
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Chapter and Conference Paper
Multifunctional Drug Nanosystems: A Summary of Recent Researches at IMS/VAST
The main task of nanomedicine is to fabricate, normally by chemical engineering, nanoscale systems that can play various functions of both diagnosis and treatment. This report aims to present some researches, ...
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Article
Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium
Phosphatase and tensin homolog (PTEN) is one of the most frequently mutated tumor suppressor genes in cancers. PTEN has a central role in phosphatidylinositol (3,4,5)-trisphosphate (PIP3) signaling and convert...
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Article
Control with constraints for linear stationary systems: An interpolation approach
We propose a new approach to controlling a discrete linear stationary system with a polyhedral constraint on the state and input. The basic idea is to use interpolation. The control law has both explicit and i...
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Chapter and Conference Paper
Adaptation of the Service Self Checklist for Industrial Product-Service Systems
This paper proposes a new approach to evaluate potential IPS2 using the Service Self Checklist (SSC). The SSC enables an effective and reasonable evaluation of services in multiple aspects. To confirm the applica...
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Chapter
Endoreduplication and Programmed Cell Death in the Cereal Endosperm
Endoreduplication and programmed cell death are important processes during the development and maturation of cereal endosperm. Endoreduplication results in the formation of multiple copies of each chromoso...
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Chapter
Welche Diagnostik ist nach erfolgreicher medikamentös-konservativer Therapie einer akuten unkomplizierten Divertikulitis durchzuführen?
Divertikulose ist ein häufiger Befund in der westeuropäischen Bevölkerung. Es wird geschätzt, dass ca. 5-10% aller Personen über 45 Jahre und ca. 80% aller Personen über 85 Jahre Divertikelträger sind. Eine sy...
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Chapter
BONSAI: A pragmatic approach to Logic Synthesis and Formal Verification
This paper describes the large scale application of logic synthesis and formal verification to the design of the CPU and caches of the high-end series of the Bull DPS7000 mainframe family. The logic CAD suite ...