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Article
The insulinotropic effect of endothelin-1 is mediated by glucagon release from the islet alpha cells
Aims/hypothesis. The circulating concentrations of endothelin-1 (ET-1), a peptide derived from endothelium, are increased in hypertension and diabetes. Endothelin-1 has recently been shown to be ...
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Article
35th Annual Meeting of the European Association for the Study of Diabetes
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Article
Effects of the hypoglycaemic drugs repaglinide and glibenclamide on ATP-sensitive potassium-channels and cytosolic calcium levels in Β TC3 cells and rat pancreatic beta cells
The present study demonstrates the action of the hypoglycaemic drugs repaglinide and glibenclamide in cultured newborn rat islet cells and mouse ΒTC3 cells. In cell-attached membrane patches of newborn rat islet ...
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Article
Purification and Characterization of IgM-like Immunoglobulin from Turbot (Scophthalmus maximus L.)
A total of 40 turbot (Scophthalmus maximus) were immunized 3 times during a 3 months period using DNP-HSA whereafter serum samples were collected and pooled. Specific immunoglobulins (Ig) were affinity purified o...
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Article
On the effects of human galanin in man
Human galanin was recently isolated and sequenced and was found to differ from porcine galanin, hitherto used for studies in humans, in several important respects. We therefore synthesized and purified human g...
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Chapter
Modern concepts of diabetes and its pathogenesis
Diabetes mellitus affects a large number of individuals and represents a syndrome which is characterized by chronic hyperglycemia. Since blood glucose is controlled by a number of mechanisms, several abnormali...