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  1. No Access

    Article

    Evaluation of flexible ureteroscope with an omni-directional bending tip, using a JOYSTICK unit (URF-Y0016): an ex-vivo study

    To compare the range of reach of our newly designed omni-directional ureteroscope (URF-Y0016), compared to the commonly used URF-P6, FlexX2s, and LithoVue™ scopes, in the upper, middle, and lower calyces in an...

    T. Inoue, S. Okada, S. Hamamoto, H. Miura, J. Matsuzaki… in World Journal of Urology (2021)

  2. No Access

    Article

    Response of river water chemistry to changing atmospheric environment and sulfur dynamics in a forested catchment in central Japan

    Reduction of atmospheric sulfur (S) deposition and recovery of terrestrial ecosystems from acidification are matters of concerns in Asia. The Lake Ijira catchment (IJR) is located in the downwind region of the...

    Hiroyuki Sase, M. Takahashi, K. Matsuda, K. Sato, T. Tanikawa… in Biogeochemistry (2019)

  3. No Access

    Article

    Lower incidence of inguinal hernia after radical prostatectomy using open gasless endoscopic single-site surgery

    Inguinal hernia is one of the long-term complications requiring surgical interventions after retropubic radical prostatectomy (RRP), and its incidence has been reported to range from 12 to 21%. The number of o...

    H Fukuhara, H Nishimatsu, M Suzuki, T Fujimura… in Prostate Cancer and Prostatic Diseases (2011)

  4. Article

    Open Access

    Multifunctional transcription factor TFII-I is an activator of BRCA1 function

    The TFII-I is a multifunctional transcriptional factor known to bind specifically to several DNA sequence elements and to mediate growth factor signalling. A microdeletion at the chromosomal location 7q11.23 e...

    M Tanikawa, O Wada-Hiraike, S Nakagawa, A Shirane, H Hiraike… in British Journal of Cancer (2011)

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  5. No Access

    Article

    Maximum tumor diameter: a simple independent predictor for biochemical recurrence after radical prostatectomy

    Previous studies have suggested that maximum tumor diameter (MTD) is a predictor of PSA recurrence or biochemical recurrence (BCR) in prostate cancer after radical prostatectomy (RP). The significance of MTD i...

    H Fukuhara, H Kume, M Suzuki, T Fujimura… in Prostate Cancer and Prostatic Diseases (2010)

  6. Article

    Open Access

    Identification of DBC1 as a transcriptional repressor for BRCA1

    DBC1/KIAA1967 (deleted in breast cancer 1) is a putative tumour-suppressor gene cloned from a heterozygously deleted region in breast cancer specimens. Caspase-dependent processing of DBC1 promotes apoptosis, and...

    H Hiraike, O Wada-Hiraike, S Nakagawa, S Koyama, Y Miyamoto… in British Journal of Cancer (2010)

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  7. No Access

    Article

    Long-term Trends in Surface Water Quality of Five Lakes in Japan

    Since 1983, the Ministry of the Environment of Japan has conducted nation-wide acid deposition surveys. To investigate the effects of acid deposition on surface water, we used the nonparametric Mann–Kendall te...

    T. Yamada, T. Inoue, H. Fukuhara, O. Nakahara… in Water, Air, & Soil Pollution: Focus (2007)

  8. No Access

    Chapter

    Long-term Trends in Surface Water Quality of Five Lakes in Japan

    Since 1983, the Ministry of the Environment of Japan has conducted nation-wide acid deposition surveys. To investigate the effects of acid deposition on surface water, we used the nonparametric Mann—Kendall te...

    T. Yamada, T. Inoue, H. Fukuhara, O. Nakahara… in Acid Rain - Deposition to Recovery (2007)

  9. No Access

    Article

    Reg I-knockout mice reveal its role in regulation of cell growth that is required in generation and maintenance of the villous structure of small intestine

    Reg I (regenerating gene product I) is a growth factor that plays a central role in the generation and regeneration of the gastric mucosal architecture. On the other hand, mouse Reg I mRNA is expressed at the hig...

    T Ose, Y Kadowaki, H Fukuhara, H Kazumori, S Ishihara, J Udagawa, H Otani… in Oncogene (2007)

  10. No Access

    Article

    Mobilization of arsenic in groundwater of Bangladesh: evidence from an incubation study

    The extensive extraction of arsenic (As)-contaminated groundwaters for drinking, household and agricultural purposes represents a serious health concern in many districts of Bangladesh. This laboratory-based i...

    H. M. Anawar, J. Akai, T. Yoshioka, E. Konohira… in Environmental Geochemistry and Health (2006)

  11. No Access

    Article

    Efficacy of ivermectin for chronic strongyloidiasis: two single doses given 2 weeks apart

    We assessed the efficacy and adverse effects of ivermectin for the treatment of chronic strongyloidiasis. Fifty patients were treated with a single dose of ivermectin at approximately 200 μg/kg, and the dose ...

    O. Zaha, T. Hirata, F. Kinjo, A. Saito… in Journal of Infection and Chemotherapy (2002)

  12. Article

    Construction of human–rodent hybrid cells containing single transferable fragments of human chromosome 10p

    The introduction of chromosome 10p into human glioblastoma or prostate cancer cells has been demonstrated to suppress their malignant phenotype, suggesting the presence of glioma or prostate tumor suppressor ...

    Y. Murakami, H. Uejima, H. Fukuhara, T. Maruyama, M. Oshimura… in Journal of Human Genetics (2000)

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  13. No Access

    Article

    Differentially expressed mRNAs in androgen-independent but not androgen-dependent Shionogi carcinoma

    Recently, a new and highly effective method termed suppressive subtractive hybridization (SSH) has been introduced to clone differentially expressed mRNAs. Genes expressed in androgen-independent but not in a...

    T. Takeuchi, H. Nishimatsu, T. Ueki, T. Kajiwara, H. Fukuhara… in Urological Research (2000)

  14. Article

    The Yeast Genome Directory

    This directory was made possible by a unique international collaboration between the 633 scientists whose names appear below. It represents both the first published description of the complete sequence of most...

    A. Goffeau, R. Aert, M. L. Agostini-Carbone, A. Ahmed, M. Aigle, L. Alberghina… in Nature (1997)

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  15. No Access

    Article

    The Kluyveromyces lactis equivalent of casein kinase I is required for the transcription of the gene encoding the low-affinity glucose permease

    The RAG8 gene of Kluyveromyces lactis, which is one of the genes controlling the expression of the low-affinity carrier gene RAG1, has been cloned by in vivo complementation of the rag8 mutation. The sequence of...

    J. Blaisonneau, H. Fukuhara, M. Wésolowski-Louvel in Molecular and General Genetics MGG (1997)

  16. No Access

    Article

    Thromboembolic Pulmonary Hypertension Due to Disseminated Fibromuscular Dysplasia

    We present two patients with thromboembolic pulmonary hypertension associated with unusual complications probably caused by disseminated fibromuscular dysplasia (FMD) or FMD-like vascular lesions. Intimal fibr...

    H. Fukuhara, H. Kitayama, T. Yokoyama, H. Shirotani in Pediatric Cardiology (1996)

  17. No Access

    Article

    Complete DNA sequence of yeast chromosome XI

    The complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome XI has been determined. In addition to a compact arrangement of potential protein coding sequences, the 666,448-base-pair sequence has re...

    B. Dujon, D. Alexandraki, B. André, W. Ansorge, V. Baladron, J. P. G. Ballesta… in Nature (1994)

  18. No Access

    Article

    The complete DNA sequence of yeast chromosome III

    The entire DNA sequence of chromosome III of the yeast Saccharomyces cerevisiae has been determined. This is the first complete sequence analysis of an entire chromosome from any organism. The 315-kilobase sequen...

    S. G. Oliver, Q. J. M. van der Aart, M. L. Agostoni-Carbone, M. Aigle… in Nature (1992)

  19. No Access

    Article

    Stable Multicopy Vectors for High–Level Secretion of Recombinant Human Serum Albumin by Kluyveromyces Yeasts

    We have designed stable pKD1 derivatives for efficient secretion of recombinant human serum albumin (rHSA) by industrial strains of Kluyveromyces yeasts. A comparison of this multi–copy expression system with iso...

    R. Fleer, P. Yeh, N. Amellal, I. Maury, A. Fournier, F. Bacchetta… in Bio/Technology (1991)

  20. No Access

    Article

    Distribution of mitochondrial r1-type introns and the associated open reading frame in the yeast genus Kluyveromyces

    We have sequenced the intron in the large subunit ribosomal RNA gene from the mitochondrion of Kluyveromyces lactis. It is a typical group I intron but, unlike the corresponding intron (r1) in Saccharomyces cerev...

    C. Wilson, H. Fukuhara in Current Genetics (1991)

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