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  1. No Access

    Article

    Comparison of the efficacy of 177Lu-EDTMP, 177Lu-DOTMP and 188Re-HEDP towards bone osteosarcoma: an in vitro study

    Among the radiopharmaceuticals harnessed for palliation of bone pain in osseous metastases patients, 177Lu labeled phosphonates such as EDTMP (Ethylene diamine tetramethylene phosphonic acid) as well as DOTMP (1,...

    Chandan Kumar, Rohit Sharma, Kusum Vats… in Journal of Radioanalytical and Nuclear Che… (2019)

  2. No Access

    Article

    Preparation and preliminary evaluation of a tris-metronidazole-99mTc(CO)3 complex for targeting tumor hypoxia

    Conventional 99mTc-radiopharmaceuticals for the detection of tumor hypoxia generally possess a single nitroimidazole moiety. Herein, we report the synthesis and evaluation of a 99mTc-complex with three-nitroimida...

    Madhava B. Mallia, Anupam Mathur… in Journal of Radioanalytical and Nuclear Che… (2018)

  3. No Access

    Article

    A Systematic Comparative Evaluation of 68Ga-Labeled RGD Peptides Conjugated with Different Chelators

    The present paper reports a systematic study on the effect of bifunctional chelators (BFC) namely, NOTA, DOTA, and DTPA, on the radiochemical formulation, in vitro stability, and in vivo biological properties of

    Akanksha Jain, Sudipta Chakraborty, H. D. Sarma… in Nuclear Medicine and Molecular Imaging (2018)

  4. No Access

    Article

    Formulation and radiochemical evaluation of a freeze-dried mixed peptide kit for the preparation of 68Ga-labeled peptides for PET imaging of somatostatin receptor positive neuroendocrine cancers

    68Ga-labeled DOTA-coupled somatostatin analogue peptides are regularly being used for the PET imaging of patients suspected to be suffering from various types of neuroendocrine cancers over-expre...

    Tapas Das, Mohini Bhadwal, H. D. Sarma… in Journal of Radioanalytical and Nuclear Che… (2014)

  5. No Access

    Article

    Synthesis and evaluation of a phenylbenzothiazole-based 99mTc(CO)3-radiotracer for possible application in imaging of β-amyloid plaques in Alzheimer’s disease

    The 2-phenyl benzothiazole pharmacophore is known to have high affinity for amyloid beta (Aβ) and is therefore derivatized, to [N-(4′-benzothiazol-pyridin-2-yl-methyl-amino)-acetic acid (BTPAA)] for radiolabeling...

    Drishty Satpati, Aruna Korde, H. D. Sarma… in Journal of Radioanalytical and Nuclear Che… (2014)

  6. No Access

    Article

    Radiolanthanide-labeled HA particles in the treatment of rheumatoid arthritis: ready-to-use cold kits for rapid formulation in hospital radiopharmacy

    Hydroxyapatite (HA) [Ca10(PO4)6(OH)2] particles radiolabeled with a variety of β− emitting lanthanide radionuclides and also pseudolanthanide 90Y have been proposed for the treatment of arthritis. A ready-to-use ...

    Sudipta Chakraborty, K. V. Vimalnath… in Journal of Radioanalytical and Nuclear Che… (2014)

  7. No Access

    Article

    Preparation of DOTA-TATE and DOTA-NOC freeze-dried kits for formulation of patient doses of 177Lu-labeled agents and their comparison for peptide receptor radionuclide therapy application

    The objective of the present work is to prepare freeze-dried DOTA-TATE and DOTA-NOC kits for the easy and convenient preparation of patient doses of 177Lu-DOTA-TATE and 177Lu-DOTA-NOC, respectively at the hospita...

    Tapas Das, Mohini Bhadwal, Sharmila Banerjee… in Journal of Radioanalytical and Nuclear Che… (2014)

  8. No Access

    Article

    Preparation of 125I-Lanreotide and its biodistribution in murine model of melanoma

    Lanreotide, a somatostatin analogue, was radioiodinated with 125I to explore the possibility of using 123I labeled lanreotide as a diagnostic radiopharmaceutical for tumors overexpressing somatostatin (SST) recep...

    U. Pandey, A. Mukherjee, G. Samuel… in Journal of Radioanalytical and Nuclear Che… (2008)

  9. No Access

    Article

    Potential of radioiodinated anti cancer compounds of natural origin for cancer therapy

    Plumbagin and Quercetin are naturally occurring compounds which exhibit anti-cancerous activity. To evaluate the effect of radioiodination on cytotoxicity, both Plumbagin and Quercetin were radioiodinated with 12...

    U. Pandey, K. Bapat, G. Samuel, H. D. Sarma… in Journal of Radioanalytical and Nuclear Che… (2007)

  10. No Access

    Article

    90Y-DOTA-Lanreotide: A potential agent for targeted therapy

    Several human tumors such as neuroendocrine tumors, medullary thyroid carcinoma, etc., express somatostatin receptors which specifically bind somatostatin and its analogues such as lanreotide, octreotide, etc....

    U. Pandey, S. Banerjee, A. Mukherjee… in Journal of Radioanalytical and Nuclear Che… (2007)

  11. No Access

    Article

    Preparation and Pharmacokinetic Evaluation of Iodine-125 Labeled Alphamethyl-L-Tyrosine

    Cerebral amino acid metabolism is known to be associated with various psychosomatic disorders. 3-(123I)iodo-L-alpha methyl tyrosine (123I-L-AMT) is an alternative to the PET radiopharmaceutical, 11C- thymidine, f...

    A. Korde, M. Venkatesh, H. D. Sarma… in Journal of Radioanalytical and Nuclear Che… (2000)

  12. No Access

    Article

    Preparation of125I labeled testosterone derivatives for use in radioimmunoassays

    Three different radiotracers of testosterone incorporating125I at position 3 or 19 were prepared and tested for usability in radioimmunoassays employing the antisera raised at our laboratory. Histamine was radioi...

    S. Grace, V. Meera, S. A. Balakrishnan… in Journal of Radioanalytical and Nuclear Che… (1997)

  13. No Access

    Article

    Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes

    Tocotrienols from palm oil showed significant ability to inhibit oxidative damage induced by ascorbate-Fe2+ and photosensitization, involving different mechanisms, in rat liver microsomes. The tocotrienol-rich...

    J.P. Kamat, H.D. Sarma, T.P.A. Devasagayam… in Molecular and Cellular Biochemistry (1997)