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Article
Multidisciplinary analysis of cancer-related fatigue at the time of diagnosis: preliminary results of the BIOCARE FActory cohort
Cancer-related fatigue (CRF) is a common side effect of cancer and cancer treatment that significantly impairs the quality of life and can persist for years after treatment completion. Although fatigue is ofte...
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Article
Open AccessBuilding a biopsychosocial model of cancer-related fatigue: the BIOCARE FActory cohort study protocol
Cancer-related fatigue (CRF) is the most common side effect of cancer and cancer treatment. CRF prevalence is up to 50% in breast cancer patients and can continue several years after cancer remission. This per...
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Article
Handgrip fatiguing exercise can provide objective assessment of cancer-related fatigue: a pilot study
As a subjective symptom, cancer-related fatigue is assessed via patient-reported outcomes. Due to the inherent bias of such evaluation, screening and treatment for cancer-related fatigue remains suboptimal. Th...
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Article
Open AccessEvaluation in usual practice of the bevacizumab-FOLFIRI combination for the first-line treatment of patients with unresectable metastatic colorectal cancer treated in 2006: focus on resected patients and oncogeriatrics
En 2006, bevacizumab-FOLFIRI représente la thérapie ciblée administrable dès la première ligne chez les patients porteurs d’un cancer colorectal métastatique non opérable. Une série homogène de 111 patients co...
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Article
Les traitements antitumoraux chez les patients traités pour une pathologie psychiatrique
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Chapter and Conference Paper
Administration sous-cutanée du trastuzumab chez des patientes avec cancer du sein HER2 positif de stade I–III : résultats cliniques et développement
Le trastuzumab (Herceptin®) est un composant clé du traitement standard des patientes (pts) avec cancer du sein (CS) précoce HER2 positif [1] et est autorisé en administration intraveineuse (IV). La dose de charg...
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Article
Open AccessPrognostic nomogram to predict progression-free survival in patients with platinum-sensitive recurrent ovarian cancer
Patients with platinum-sensitive recurrent ovarian cancer are a heterogeneous group, and it is not possible to accurately predict the progression-free survival (PFS) in these patients. We developed and validat...
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Article
Étude de phase IV de pharmacovigilance portant sur la toxicité cardiaque du trastuzumab en néoadjuvant et adjuvant dans le cancer du sein. Analyse conduite par l’Observatoire des Médicaments et des Innovations Thérapeutiques de Bretagne et des Pays de la Loire (OMIT B PL)
The “Observatoire des Médicaments et Innovations Thérapeutiques OMIT” directed by ARH Bretagne et Pays de la Loire, has been created in 2002. He’s specialized in oncology, monitoring a few drugs every year and...
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Article
Evaluation of oral versus intravenous dose of vinorelbine to achieve equivalent blood exposures in patients with solid tumours
Patient’s preference is for oral chemotherapy when both oral and i.v. are available, provided that efficacy is equivalent. Reliable switch from oral to i.v. is possible if correspondence between respective dos...
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Article
Open AccessPhase II multicentre study of docetaxel plus 5-fluorouracil in patients with anthracycline-pretreated metastatic breast cancer
The purpose of the study was to determine the efficacy and safety of docetaxel plus continuous infusion of 5-fluorouracil (5-FU) in patients with metastatic breast cancer previously treated with anthracyclines...
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Chapter
Molecular Motions in Catenands and Catenates Studied by 13C NMR Relaxation Times
Molecular motions in catenands and catenates were studied by 13C NMR relaxation times and were compared to those of the free macrocycles. The macrocycles are less mobile when interlocked in a catenand or in a cat...
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Article
Antioxidant activity of plasma from subjects with and without senile cataract
The relationship between overall plasma antioxidant activity and senile cataract was examined in 148 subjects aged 37–90 years. Antioxidant activity of plasma from 52 control and 96 patients with senile catara...
