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7 Result(s)

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  1. No Access

    Article

    Pathway-based analysis of genetic susceptibility to cervical cancer in situ: HLA-DPB1 affects risk in Swedish women

    We have conducted a pathway-based analysis of genome-wide single-nucleotide polymorphism (SNP) data in order to identify genetic susceptibility factors for cervical cancer in situ. Genotypes derived from Affymetr...

    E L Ivansson, I Juko-Pecirep, H A Erlich, U B Gyllensten in Genes & Immunity (2011)

  2. No Access

    Article

    Evidence for association of the TCF7 locus with type I diabetes

    The Type I Diabetes Genetics Consortium (T1DGC) has collected thousands of multiplex and simplex families with type I diabetes (T1D) with the goal of identifying genes involved in T1D susceptibility. These fam...

    H A Erlich, A M Valdes, C Julier, D Mirel, J A Noble in Genes & Immunity (2009)

  3. No Access

    Article

    Association analysis of SNPs in the IL4R locus with type I diabetes

    The Type I Diabetes Genetics Consortium (T1DGC) has collected thousands of multiplex and simplex families with type I diabetes (T1D) with the goal of identifying genes involved in T1D susceptibility. These fam...

    H A Erlich, K Lohman, S J Mack, A M Valdes, C Julier, D Mirel… in Genes & Immunity (2009)

  4. No Access

    Article

    MHC loci affecting cervical cancer risk: distinguishing the effects of HLA-DQB1 and non-HLA genes TNF, LTA, TAP1 and TAP2

    Cervical cancer has been associated with specific human leukocyte antigen (HLA) haplotypes/alleles and with polymorphisms at the nearby non-HLA loci TNF, LTA, TAP1 and TAP2. Distinguishing effects of individual l...

    E L Ivansson, J J Magnusson, P K E Magnusson, H A Erlich… in Genes & Immunity (2008)

  5. No Access

    Article

    Differential effects of DRB1*0301 and DQA1*0501-DQB1*0201 on the activation and progression of islet cell autoimmunity

    Autoimmune diabetes shows extreme variation in age of onset and clinical presentation, although most studies have been done in children with the most severe subtype. Disease risk is strongly associated with HL...

    E Eller, P Vardi, K K McFann, S R Babu, L Yu, T L Bugawan, H A Erlich… in Genes & Immunity (2007)

  6. No Access

    Article

    Multifactor dimensionality reduction reveals gene–gene interactions associated with multiple sclerosis susceptibility in African Americans

    Multiple sclerosis (MS) is a common disease of the central nervous system characterized by inflammation, myelin loss, gliosis, varying degrees of axonal pathology, and progressive neurological dysfunction. Mul...

    D Brassat, A A Motsinger, S J Caillier, H A Erlich, K Walker… in Genes & Immunity (2006)

  7. No Access

    Article

    Analysis of IL4R haplotypes in predisposition to multiple sclerosis

    We have investigated the association of multiple sclerosis (MS) with polymorphisms in the IL4R gene in 332 single-case MS families. IL4R encodes a subunit of the interleukin-4 receptor, a molecule important for T...

    D B Mirel, L F Barcellos, J Wang, S L Hauser, J R Oksenberg, H A Erlich in Genes & Immunity (2004)