Skip to main content

13 Result(s)

within English Remove this filter Biomedicine Remove this filter Immunology Remove this filter H. A. Erlich Remove this filter

and

  1. No Access

    Article

    Pathway-based analysis of genetic susceptibility to cervical cancer in situ: HLA-DPB1 affects risk in Swedish women

    We have conducted a pathway-based analysis of genome-wide single-nucleotide polymorphism (SNP) data in order to identify genetic susceptibility factors for cervical cancer in situ. Genotypes derived from Affymetr...

    E L Ivansson, I Juko-Pecirep, H A Erlich, U B Gyllensten in Genes & Immunity (2011)

  2. No Access

    Article

    Evidence for association of the TCF7 locus with type I diabetes

    The Type I Diabetes Genetics Consortium (T1DGC) has collected thousands of multiplex and simplex families with type I diabetes (T1D) with the goal of identifying genes involved in T1D susceptibility. These fam...

    H A Erlich, A M Valdes, C Julier, D Mirel, J A Noble in Genes & Immunity (2009)

  3. No Access

    Article

    Association analysis of SNPs in the IL4R locus with type I diabetes

    The Type I Diabetes Genetics Consortium (T1DGC) has collected thousands of multiplex and simplex families with type I diabetes (T1D) with the goal of identifying genes involved in T1D susceptibility. These fam...

    H A Erlich, K Lohman, S J Mack, A M Valdes, C Julier, D Mirel… in Genes & Immunity (2009)

  4. No Access

    Article

    MHC loci affecting cervical cancer risk: distinguishing the effects of HLA-DQB1 and non-HLA genes TNF, LTA, TAP1 and TAP2

    Cervical cancer has been associated with specific human leukocyte antigen (HLA) haplotypes/alleles and with polymorphisms at the nearby non-HLA loci TNF, LTA, TAP1 and TAP2. Distinguishing effects of individual l...

    E L Ivansson, J J Magnusson, P K E Magnusson, H A Erlich… in Genes & Immunity (2008)

  5. No Access

    Article

    Differential effects of DRB1*0301 and DQA1*0501-DQB1*0201 on the activation and progression of islet cell autoimmunity

    Autoimmune diabetes shows extreme variation in age of onset and clinical presentation, although most studies have been done in children with the most severe subtype. Disease risk is strongly associated with HL...

    E Eller, P Vardi, K K McFann, S R Babu, L Yu, T L Bugawan, H A Erlich… in Genes & Immunity (2007)

  6. No Access

    Article

    Multifactor dimensionality reduction reveals gene–gene interactions associated with multiple sclerosis susceptibility in African Americans

    Multiple sclerosis (MS) is a common disease of the central nervous system characterized by inflammation, myelin loss, gliosis, varying degrees of axonal pathology, and progressive neurological dysfunction. Mul...

    D Brassat, A A Motsinger, S J Caillier, H A Erlich, K Walker… in Genes & Immunity (2006)

  7. No Access

    Article

    Analysis of IL4R haplotypes in predisposition to multiple sclerosis

    We have investigated the association of multiple sclerosis (MS) with polymorphisms in the IL4R gene in 332 single-case MS families. IL4R encodes a subunit of the interleukin-4 receptor, a molecule important for T...

    D B Mirel, L F Barcellos, J Wang, S L Hauser, J R Oksenberg, H A Erlich in Genes & Immunity (2004)

  8. No Access

    Chapter

    The DQ Loci

    The MHC class II DQ molecule is composed of an α-chain, encoded by the DQA1 locus and a β-chain, encoded by the DQB1 locus. In contrast to the DR and DP molecules, both the α-chain and the β-chain are polymorphic...

    U. Gyllensten, T. Bergström, H. A. Erlich in Molecular Biology and Evolution of Blood G… (1997)

  9. No Access

    Article

    Nomenclature for factors of theHLA system, 1991

    J. G. Bodmer, E. D. Albert, W. F. Bodmer, B. Dupont, H. A. Erlich… in Immunogenetics (1992)

  10. No Access

    Chapter and Conference Paper

    Chairman’s Summing up Evolutionary Analysis of HLA Class II Polymorphisms

    As I said earlier this morning, rather than use this time for summary of the very interesting talks we have heard, I thought I would very briefly go through some of the evolutionary analysis and just discuss h...

    H. A. Erlich in The Molecular Biology of Autoimmune Disease (1990)

  11. No Access

    Chapter and Conference Paper

    Introduction

    As you know in humans the general polymorphisms are HLA DR DQ and DP and perhaps one thing that we can think about — is there any different functions to these different alpha beta heterodimers. As you know, ma...

    H. A. Erlich in The Molecular Biology of Autoimmune Disease (1990)

  12. No Access

    Chapter

    Analysis of HLA-DP Allelic Sequence Polymorphism Using the In Vitro Enzymatic Amplification of DPα and DPβ Loci

    Accurate ty** of the HLA-DP antigens can provide useful information when considering allogeneic bone marrow transplantation. As with the HLA-DR and DQ antigens, the DP molecules may also play a role in susce...

    T. L. Bugawan, G. T. Horn, J. A. Hansen, E. M. Mickelson… in Immunobiology of HLA (1989)

  13. No Access

    Chapter and Conference Paper

    HLA Ty** on Single Human Hairs: DNA Probes to Enzymatically Amplified Genes

    A single human hair does not contain enough DNA to allow detection of DNA polymorphisms routinely (1). However, a new technique (2) is available that can greatly amplify, in-vitro, short regions of DNA and can de...

    R. G. Higuchi, C. H. von Beroldingen… in Advances in Forensic Haemogenetics (1988)