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Article
Inhibition of pulmonary cancer progression by epidermal growth factor receptor-targeted transfection with Bcl-2 and survivin siRNAs
Clinical application of small interfering RNA (siRNA) in cancer therapy has been limited by the lack of an efficient systemic siRNA delivery system. In this report we describe an efficient siRNA delivery syste...
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Article
Investigation on the flame characteristics in a PCCI engine using endoscope system with micro-cassegrain
Diesel engines are most frequently used in vehicles because of their high efficiency and durability. However, nitrogen oxide (NOx) and particulate matter (PM) from diesel engines are became problem. Recently, ...
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Article
Driver propensity characterization for different forward collision warning times
The forward collision warning system, which warns danger to the driver after sensing possibility of crash in advance, has been actively studied recently. Such systems developed until now give a warning, regard...
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Article
Open AccessA macrophage-specific synthetic promoter for therapeutic application of adiponectin
Foam cell formation from macrophage is a major cause of atherosclerosis. An efficient macrophage-specific promoter is required for the targeting to macrophages. In this study, we develop a macrophage-specific ...
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Article
Hydroplaning simulation of a tire in thin water using fem and an estimation method and its application to skid number estimation
To simulate the hydroplaning of a tire, many analytical studies have been performed using commercial explicit FE (Finite Element) codes such as MSC.DYTRAN and LS-DYNA. However, most previous studies on this su...
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Article
Design methodology to reduce the chest deflection in US NCAP and EURO NCAP tests
There have not been many studies on the factors that affect chest deflection, although the US NCAP thoracic injury criterion was recently shifted from the 3-msec clip to chest deflection. This study explored t...
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Article
Combining stress relaxation and rheometer test results in modeling a polyurethane stopper
In general, polymers show time-dependent stress-strain responses. The responses can be measured in a time-based test (e.g. a stress relaxation test) or a frequency-based test (e.g. a rheometer test). In a stre...
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Article
Hydroplaning simulations for tires using FEM, FVM and an asymptotic method
Hydroplaning tires have been frequently simulated using commercial explicit FEM (Finite Element Method) codes. However, these simulations are slow, and the result of the lift force is so oscillatory that the h...
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Article
Stochastic analysis of the variation in injury numbers of automobile frontal crash tests
Although automobile crash test data have a comparatively large variation because of the complexity of the tests, only a limited number of crash tests are usually conducted due to monetary and time limitations....
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Article
Development of the FMECA process and analysis methodology for railroad systems
FMECA (Failure Modes, Effects and Criticality Analysis) is a procedure used to identify potential failure modes, determine causes and effects of failure modes and mitigate or remove its effects on system funct...
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Chapter and Conference Paper
Long-term In vivo Biocompatibility Evaluation of MEMS Retinal Tack for Retinal Prosthesis
In this paper, long-term (1 year) in vivo biocompatibility evaluation of silicon retinal tack is presented. Such a long-term in vivo experiment of biocompatibility has not been reported so far in the retinal pros...
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Article
Hydroplaning simulation for a straight-grooved tire by using FDM, FEM and an asymptotic method
Much research has been conducted to simulate the hydroplaning phenomenon of tires by using commercial explicit FEM (finite element method) codes such as MSC.Dytran and LS-DYNA. However, it takes a long time to...
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Article
Consideration of the frictional force on the crack surface and its implications for durability of tires
In order to find out a physical quantity which controls the fatigue life of a structure and to predict the fatigue life of tires, a finite element simulation methodology to use the cracking energy density (CED...
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Chapter and Conference Paper
Flow Localization in Porous Solids with Pressure-Sensitive Matrices
Pressure-sensitive yielding has been observed for polymers, for example, see Sternstein and Ongchin[1] and Spitzig and Richmond[2]. The pressure-sensitive yielding has been approximately described by Coulomb’s...
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Article
The effects of rate sensitivity and plastic potential surface curvature on plastic flow localization in porous solids
Plastic flow localization in porous elastic-viscoplastic solids is analyzed with an emphasis on the effects of material rate sensitivity and plastic potential surface curvature. The effect of rate sensitivity ...
