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Article
Bloodstream infection in paediatric cancer centres—leukaemia and relapsed malignancies are independent risk factors
In a prospective multicentre study of bloodstream infection (BSI) from November 01, 2007 to July 31, 2010, seven paediatric cancer centres (PCC) from Germany and one from Switzerland included 770 paediatric ca...
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Article
Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases
The purpose of this study was the appraisal of the clinical and functional consequences of germline mutations within the gene for the IL-2 inducible T-cell kinase, ITK. Among patients with Epstein-Barr virus-d...
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Article
Total body MRI-governed involved compartment irradiation combined with high-dose chemotherapy and stem cell rescue improves long-term survival in Ewing tumor patients with multiple primary bone metastases
We examined the role of total body magnetic resonance imaging (TB-MRI)-governed involved compartment irradiation (ICI) and high-dose chemotherapy (HDC), followed by stem cell rescue (SCR) in patients with high...
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Article
Diagnostic and therapeutic implications of neurological complications following paediatric haematopoietic stem cell transplantation
Neurological complications are a relevant cause of morbidity and mortality after haematopoietic stem cell transplantation (SCT). We retrospectively analysed neurological complications of 165 paediatric patient...
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Article
Piperacillin-tazobactam in pediatric cancer patients younger than 25 months: a retrospective multicenter survey
Piperacillin-Tazobactam (Pip-Taz) is an evidence-based empirical treatment of febrile neutropenia in adolescents and adults. No data are available in pediatric cancer patients <25 months of age. In this retros...
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Article
Erratum: Defibrotide in the treatment of children with veno-occlusive disease (VOD): a retrospective multicentre study demonstrates therapeutic efficacy upon early intervention
Correction to: Bone Marrow Transplantation (2004) 33, 189–195. doi:10.1038/sj.bmt.1704329; Published online: 8 December 2003. The author names and affiliations were published incorrectly; the correct version i...
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Article
Defibrotide in the treatment of children with veno-occlusive disease (VOD): a retrospective multicentre study demonstrates therapeutic efficacy upon early intervention
Veno-occlusive disease (VOD) of the liver is a complication observed particularly in patients undergoing hematopoietic stem cell transplantation (HSCT). Defibrotide (DF) is a polydeoxyribonucleotide with aptam...
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Article
Erratum: High-dose chemotherapy with autologous stem cell rescue in children with nephroblastoma
Bone Marrow Transplantation 2003;31:893–898 The authors have realised that a wrong figure was included with the paper above. The correct figure is below (Figure 1).
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Article
High-dose chemotherapy with autologous stem cell rescue in children with nephroblastoma
Children with Wilms tumor who have a particular risk of failure at relapse or at primary diagnosis were treated with high-dose chemotherapy (HDC) and autologous peripheral blood stem cell rescue in order to im...
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Article
In vivo cytokine responses to interleukin-2 immunotherapy after autologous stem cell transplantation in children with solid tumors
The potent immunostimulatory cytokine interleukin-2 (IL-2) has been extensively investigated for its potential to induce anti-tumor immunity in a number of tumor models. Only recently the complex interplay of ...
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Chapter
Transgenic Expression of IL-2 in Peripheral Neuroectodermal Malignancies of Childhood: In Vitro and In Vivo Effects on Lymphocyte Activation and Tumor Lysis
Posttransplantational adjuvant interleukin-2 (IL-2) therapy has previously been shown to improve the prognosis of patients with Ewing tumors. This has been attributed to a stimulation of the immune system and ...
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Article
Cure of latex allergy by bone marrow transplantation
