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Article
Social dynamics of community resilience building in the face of climate change: the case of three Scottish communities
Meeting global targets that maintain temperatures at 1.5 °C above pre-industrial levels while adapting to the growing impacts of climate change requires significant and rapid societal change. Within this conte...
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Article
Open AccessPhase III trial comparing paclitaxel poliglumex vs docetaxel in the second-line treatment of non-small-cell lung cancer
Paclitaxel poliglumex (PPX), a macromolecule drug conjugate linking paclitaxel to polyglutamic acid, reduces systemic exposure to peak concentrations of free paclitaxel. Patients with non-small-cell lung cance...
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Article
Phase 1/2 trial of autologous tumor mixed with an allogeneic GVAX® vaccine in advanced-stage non-small-cell lung cancer
Tumor vaccines composed of autologous tumor cells genetically modified to secrete granulocyte–macrophage colony-stimulating factor (GM-CSF) (GVAX®) have demonstrated clinical activity in advanced-stage non-small-...
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Chapter and Conference Paper
Student Modeling for an Intelligent Agent in a Collaborative Learning Environment
We present an application of student modeling in support of individual learning and group collaboration. The design is based on an empirical analysis of collaborative dialogs collected in earlier work. During ...
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Chapter
Somatic embryogenesis — the gate to biotechnology in conifers
“I believe [...] one could successfully cultivate artificial embryos from vegetative cells.” With this vision, Gottlieb Haberlandt closed his 1902 publication “Experiments on the culture of isolated cells”. Ba...
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Chapter
Molecular Pathological Mechanisms in NSCLC and the Assessment of Individuals with a High Risk of Develo** Lung Cancer
Lung cancer is responsible for more deaths than any other cancer, accounting for 785,000 deaths per year world wide [1]. It is the most common malignancy in males the UK. The highest incidence rates of lung ca...
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Article
p53 gene aberrations in non-small-cell lung carcinomas from a smoking population
We examined 46 non-small-cell lung carcinomas (NSCLCs) for the presence of p53 mutations in exons 4-9, positive p53 immunostaining and loss of heterozygosity (LOH) in the TP53 locus. p53 mutations were detecte...
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Article
Fractional allele loss data indicate distinct genetic populations in the development of non-small-cell lung cancer
Allelic imbalance or loss of heterozygosity (LOH) has been widely used to assess genetic instability in tumours, and high LOH on chromosome arms 3p, 9p and 17p has been considered to be a common event in non-s...
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Chapter
Research Needs in Understanding Processes of Transformation, and Dry and Wet Deposition of Atmospheric Metals
In order to better understand the transport and removal of atmospheric trace metals more knowledge in the following basic atmospheric processes is needed:
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Chapter and Conference Paper
Structural Change and Long-Term Fluctuations in Economic Growth
The last decade was and the next decades will be periods of substantial structural economic change: newly industrialized nations emerged, East Asia became a leading economic center, new products and production...
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Article
The effects of colchicine doubling of potato dihaploid X wild species hybrids on eelworm resistance and pollen ‘stainability’
Diploid potato clones (dihaploid x wild species hybrids) and their colchicine doubled, tetraploid counterparts were compared for resistance to eelworm (Globodera rostochiensis andG. pallida) and for pollen ‘stain...
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Article
Origin of Unreduced Embryo Sacs in Diploid Potatoes
THERE are clear advantages in carrying out potato breeding at the diploid level, but it is likely that the expression of maximum productivity occurs at the tetraploid level1. One way in which diploids can be brou...
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Article
Über die Resistenz von Solanum (Tuberarium)-Arten gegen europäische Rassen des Kartoffelnematoden (Heterodera rostochiensis Woll.)
63 tuber bearing Solanum species of 200 proveniencies were screened for cyst production with race A and 11 deviating (B−) races found in Scotland, Norway, The Netherlands, Germany, and Switzerland. The authors th...
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Article
Lycopersicum chilense Dun., eine Testpflanze für die beiden Kartoffelviren M und S
Lycopersicum chilense Dun. bildet mit dem M- und S-Virus deutliche und gut voncinander unterscheidbare systemische Symptome. Die Infektion mit den Viren A, F, X, Y, Tabakringflecken-(Bukett-), TMV und Rattle füh...
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Article
Kurzer Bericht Über Eine Expedition zur Sammlung von Kartoffelwildarten in den Peruanischen Lomas
Im Bereich des Gesamtareals der Wildkartoffeln stellen die “Lomas” der peruanischen Küste eine besondere pflanzengeographische Formation dar. Ihre Vegetationsperiode fällt in den Südwinter (Mai-Oktober), zu we...
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Article
The use of wild solanum species in German potato breeding of the past and today
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Article
News
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Buchbesprechungen
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Article
Über die Vererbung der Resistenz gegen den Kartoffelnematoden (Heterodera rostochiensis Woll.) in Kreuzungen vonSolanum famatinae Bitt. et Wittm. mitSolanum tuberosum L. und mitS. chacoense Bitt.
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Solanum famatinae erwies sich in allen Testen als resistent gegen die allgemeine Rasse und die abweichenden ...
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Article
Die Praxis der Züchtung auf Infektions-resistenz und Extremer Resistenz (Immunität) Gegen das Y-Virus der Kartoffel
Es werden die Methoden der Züchtung auf Infektionsresistenz gegen das Y-Virus und auf extremer Resistenz (Immunität) gegen das Y- und das A-Virus beschrieben. Erstere findet sich bereits in zahlreichen T-, D- ...