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    Article

    EMMPRIN regulates the canonical Wnt/β-catenin signaling pathway, a potential role in accelerating lung tumorigenesis

    Advances in the field of tumor biology have identified that tumor cells co-opt developmental signaling pathways of embryonic stem cells and thus gain the ability to proliferate, differentiate and alter cell–ce...

    S S Sidhu, R Nawroth, M Retz, H Lemjabbar-Alaoui, V Dasari, C Basbaum in Oncogene (2010)

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    Article

    Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis

    Heparan sulfate (HS) proteoglycans (HSPGs) bind to multiple growth factors/morphogens and regulate their signaling. 6-O-sulfation (6S) of glucosamine within HS chains is critical for many of these ligand interact...

    H Lemjabbar-Alaoui, A van Zante, M S Singer, Q Xue, Y -Q Wang, D Tsay, B He in Oncogene (2010)