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  1. No Access

    Article

    Overexpression of Ad5 precursor terminal protein accelerates recombinant adenovirus packaging and amplification in HEK-293 packaging cells

    Recombinant adenoviruses are one of the most common vehicles for efficient in vitro and in vivo gene deliveries. Here, we investigate whether exogenous precursor terminal protein (pTP) expression in 293 cells imp...

    N Wu, H Zhang, F Deng, R Li, W Zhang, X Chen, S Wen, N Wang, J Zhang, L Yin… in Gene Therapy (2014)

  2. No Access

    Article

    Insulin-like growth factor binding protein 5 suppresses tumor growth and metastasis of human osteosarcoma

    Osteosarcoma (OS) is the most common primary malignancy of bone. There is a critical need to identify the events that lead to the poorly understood mechanism of OS development and metastasis. The goal of this ...

    Y Su, E R Wagner, Q Luo, J Huang, L Chen, B-C He, G-W Zuo, Q Shi, B-Q Zhang… in Oncogene (2011)

  3. No Access

    Article

    Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery

    Efficacious bone regeneration could revolutionize the clinical management of bone and musculoskeletal disorders. Although several bone morphogenetic proteins (BMPs) (mostly BMP-2 and BMP-7) have been shown to ...

    Q Kang, M H Sun, H Cheng, Y Peng, A G Montag, A T Deyrup, W Jiang, H H Luu… in Gene Therapy (2004)