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    Article

    Synthesis and Antitumor Activity of Sorafenib Analogs Containing a Tetrazole Moiety

    A novel series of diaryl biuret derivatives containing a tetrazole moiety was designed and synthesized. All the target compounds were evaluated for their in vitro antitumor activity against HT-29, HepG2, MCF-7 an...

    Ye Tian, Simiao Yu, Lude Cai, Guowei Gong in Chemical Research in Chinese Universities (2019)

  2. Article

    Open Access

    Danggui Buxue Tang, an ancient Chinese herbal decoction, protects β-amyloid-induced cell death in cultured cortical neurons

    Danggui Buxue Tang (DBT) is a historical Chinese herbal decoction, and which has more than 800 years of applications. This herbal decoction solely contains two materials: Astragali Radix (AR) and Angelicae Sinens...

    Guowei Gong, Baohui Qi, Yan T. Liang in BMC Complementary and Alternative Medicine (2019)

  3. Article

    Open Access

    Flavonoids are identified from the extract of Scutellariae Radix to suppress inflammatory-induced angiogenic responses in cultured RAW 264.7 macrophages

    Scutellariae Radix (SR), also named Huangqin in China, is the dried root of Scutellaria baicalensis Georgi. Historically, the usage of SR was targeted to against inflammation. In fact, chronic inflammation has a ...

    Guowei Gong, Huaiyou Wang, **angpeng Kong, Ran Duan, Tina T. X. Dong in Scientific Reports (2018)