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Article
Open AccessUnlocking the potentials of cyanobacterial photosynthesis for directly converting carbon dioxide into glucose
Glucose is the most abundant monosaccharide, serving as an essential energy source for cells in all domains of life and as an important feedstock for the biorefinery industry. The plant-biomass-sugar route dom...
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Article
Open AccessEngineered hypermutation adapts cyanobacterial photosynthesis to combined high light and high temperature stress
Photosynthesis can be impaired by combined high light and high temperature (HLHT) stress. Obtaining HLHT tolerant photoautotrophs is laborious and time-consuming, and in most cases the underlying molecular mec...
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Article
Open AccessA miniaturized bionic ocean-battery mimicking the structure of marine microbial ecosystems
Marine microbial ecosystems can be viewed as a huge ocean-battery charged by solar energy. It provides a model for fabricating bio-solar cell, a bioelectrochemical system that converts light into electricity. ...
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Engineering Cyanobacteria Cell Factories for Photosynthetic Production of Sucrose
Biorefinery technology serves as an important alternative route to alleviate the energy and environmental crisis and to promote sustainable development. The sufficient supply of sugar feedstocks is the basis a...
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Article
Open AccessRescuing ethanol photosynthetic production of cyanobacteria in non-sterilized outdoor cultivations with a bicarbonate-based pH-rising strategy
Ethanol photosynthetic production based on cyanobacteria cell factories utilizing CO2 and solar energy provides an attractive solution for sustainable production of green fuels. However, the scaling up processes ...
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Article
Open AccessCombinatory strategy for characterizing and understanding the ethanol synthesis pathway in cyanobacteria cell factories
Photosynthetic production of chemicals and fuels by recycling CO2 in cyanobacteria is a promising solution facing energy shortage and resource declination. Ethanol is an attractive and demonstrative biofuel produ...
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Article
Develo** controllable hypermutable Clostridium cells through manipulating its methyl-directed mismatch repair system
Development of controllable hypermutable cells can greatly benefit understanding and harnessing microbial evolution. However, there have not been any similar systems developed for Clostridium, an important bacter...
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Article
Open AccessGenome replication engineering assisted continuous evolution (GREACE) to improve microbial tolerance for biofuels production
Microbial production of biofuels requires robust cell growth and metabolism under tough conditions. Conventionally, such tolerance phenotypes were engineered through evolutionary engineering using the principl...