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Article
Impact of micro-scale regular topography on cell and tissue behaviors
Physical cues of a biomaterial surface such as topography have received extensive attention due to their ease of engineering and reproducible bioeffects. Although many studies have been reported, the relations...
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Article
Open AccessAnalysis of tumor microenvironment alterations in partially responsive rectal cancer patients treated with neoadjuvant chemoradiotherapy
Achieving a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT) remains a challenge for most patients with rectal cancer. Exploring the potential of combining NCRT with immunotherapy ...
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Article
Open AccessCorrelation between hemoglobin and the risk of common malignant tumors: a 1999–2020 retrospective analysis and causal association analysis
The role of hemoglobin (HGB) in common malignant tumors remains unclear.
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Article
Relativistic configuration interaction calculations on Kα X-ray satellites of Rb XXXVI to Rb XXVIII
Multi-configuration Dirac–Hartree–Fock (MCDHF) and relativistic configuration interaction (RCI) calculations with the Breit interaction and quantum electrodynamical (QED) contributions were carried out in the ...
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Article
Open AccessGenome-wide identification and expression analysis of the KNOX family and its diverse roles in response to growth and abiotic tolerance in sweet potato and its two diploid relatives
KNOXs, a type of homeobox genes that encode atypical homeobox proteins, play an essential role in the regulation of growth and development, hormonal response, and abiotic stress in plants. However, the KNOX gene ...
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Article
Open AccessClinical significance and prospective mechanism of increased CDKN2A expression in small cell lung cancer
Although it has been shown that cyclin dependent kinase inhibitor 2A (CDKN2A) plays a significant role in a number of malignancies, its clinicopathological value and function in small cell lung cancer (SCLC) i...
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Article
Open AccessLncRNA LUESCC promotes esophageal squamous cell carcinoma by targeting the miR-6785-5p/NRSN2 axis
Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent gastrointestinal malignancies with high mortality worldwide. Emerging evidence indicates that long noncoding RNAs (lncRNAs) are involved i...
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Article
Open AccessCircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma
The oncogenic role of circRNA in cancers including esophageal cancer (EC) has been well studied. However, whether and how circRNAs are involved in cancer cell metabolic processes remains largely unknown. Here,...
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Article
Retraction Note: Two Ni(II)-Based Coordination Complexes: Crystal Structures and Treatment Activity on Neonatal Hypoxic-Ischemic Encephalopathy
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Article
Performance evaluation for the IoT-based manufacturing system in pharmacy industry
Drugs and medicine have been playing an important role in protecting human health. With economic and societal development, drugs and manufacturers will be facing higher production standards and a traceable pro...
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Article
Hessian Regularized \(L_{2,1}\) -Nonnegative Matrix Factorization and Deep Learning for miRNA–Disease Associations Prediction
Since the identification of microRNAs (miRNAs), empirical research has demonstrated their crucial involvement in the functioning of organisms. Investigating miRNAs significantly bolsters efforts related to ave...
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Article
Morphological Aesthetics Assessment of the Predicted 3D Simulation Results and the Actual Results of Breast Augmentation
Although three-dimensional (3D) simulations are becoming more common in preoperative breast augmentation planning, this does not necessarily imply that the simulated results are highly accurate.
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Article
Open AccessNMDARs activation regulates endothelial ferroptosis via the PP2A-AMPK-HMGB1 axis
N-methyl-D-aspartate receptors (NMDARs) are ligand-gated, voltage-dependent channels of the ionotropic glutamate receptor family. The present study explored whether NMDAR activation induced ferroptosis in vasc...
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Chapter and Conference Paper
Numerical Simulation Study on the Flow Influence of Multiscale Fractures During Water Flooding
Multiscale fractures consist of artificial and natural fractures are important flow channels in low-permeability oil reservoir. Due to the different flow capacity of multiscale fractures, large-scale fractures...
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Article
Ti3C2Tx/SnO2 P–N heterostructure construction boosts room-temperature detecting formaldehyde
Formaldehyde is a common atmospheric pollutant produced in industrial production and daily life. However, the traditional semiconductor formaldehyde gas sensor cannot work at room temperature, which limits its...
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Article
CDK6 is a novel predictive and prognosis biomarker correlated with immune infiltrates in multiple human neoplasms, including small cell lung carcinoma
The roles of cyclin-dependent kinase 6 (CDK6) in various cancers, including small cell lung carcinoma (SCLC), remain unclear. Here, 111,54 multi-center samples were investigated to determine the expression, clini...
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Article
Full-endoscopic lumbar discectomy via lateral superior articular process approach for treating far lateral lumbar disc herniation: a retrospective study and technical note
This study aims to evaluate the efficacy and safety of the full-endoscopic lumbar discectomy (FELD) via lateral superior articular process (LSAP) approach and full-endoscopic transforaminal discectomy (FETD) f...
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Article
ITGB4 Serves as an Identification and Prognosis Marker Associated with Immune Infiltration in Small Cell Lung Carcinoma
Integrin beta 4 (ITGB4) is a vital factor for numerous cancers. However, no reports regarding ITGB4 in small cell lung carcinoma (SCLC) have been found in the existing literature. This study systematically invest...
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Article
Open AccessEvaluation of dynamic recurrence risk for locally advanced gastric cancer in the clinical setting of adjuvant chemotherapy: a real-world study with IPTW-based conditional recurrence analysis
The long-term dynamic recurrence hazard of locally advanced gastric cancer (LAGC) in the clinical setting of adjuvant chemotherapy (ACT) remains unclear.
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Article
Comparison of robotic versus laparoscopic versus open distal gastrectomy for locally advanced gastric cancer: a prospective trial-based economic evaluation
It is largely unclear whether robotic distal gastrectomy (RDG) is cost-effective for locally advanced gastric cancer (LAGC).
