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  1. Article

    Open Access

    Neurodevelopmental risk and adaptation as a model for comorbidity among internalizing and externalizing disorders: genomics and cell-specific expression enriched morphometric study

    Comorbidity is the rule rather than the exception for childhood and adolescent onset mental disorders, but we cannot predict its occurrence and do not know the neural mechanisms underlying comorbidity. We inve...

    Nanyu Kuang, Zhaowen Liu, Gechang Yu, **nran Wu, Benjamin Becker in BMC Medicine (2023)

  2. No Access

    Article

    Disrupted long-range gene regulations elucidate shared tissue-specific mechanisms of neuropsychiatric disorders

    Neurological and psychiatric disorders have overlapped phenotypic profiles, but the underlying tissue-specific functional processes remain largely unknown. In this study, we explore the shared tissue-specifici...

    **gqi Chen, Liting Song, Anyi Yang, Guiying Dong, **ng-Ming Zhao in Molecular Psychiatry (2022)

  3. Article

    Open Access

    A global overview of genetically interpretable multimorbidities among common diseases in the UK Biobank

    Multimorbidities greatly increase the global health burdens, but the landscapes of their genetic risks have not been systematically investigated.

    Guiying Dong, Jianfeng Feng, Fengzhu Sun, **gqi Chen, **ng-Ming Zhao in Genome Medicine (2021)