Skip to main content

and
  1. No Access

    Article

    Retroflexed dens in paediatric Chiari 1 patients and implications: Single centre retrospective study

    Chiari 1 malformation and hind brain hernia can be associated with skull base and craniocervical anomalies. One of the more recently associated anomalies is a retroverted or retroflexed odontoid process or den...

    Bobby Sachdev, Vesta S. Najmi, Desiderio Rodrigues in Child's Nervous System (2024)

  2. No Access

    Article

    Traumatic disruption of dura at suture lines: a consistent finding in non-accidental head injury?

    Pasquale Gallo, Rehman Ali Baig, William B. Lo, Adam J. Oates in Child's Nervous System (2023)

  3. No Access

    Article

    Medulloblastomas, CNS embryonal tumors, and cerebellar mutism syndrome: advances in care and future directions

    Central nervous system (CNS) embryonal tumors, commonly found in pediatric patients, represent a heterogeneous mix of lesions with an overall poor (though improving) prognosis. Medulloblastomas are by far the ...

    Nirali Patel, Gregory Keating, Guirish A. Solanki, Hasan R. Syed in Child's Nervous System (2023)

  4. No Access

    Article

    Clinical features and outcome in pediatric arteriovenous malformation: institutional multimodality treatment

    Intracranial arteriovenous-malformation (AVM) is a relatively rare condition in pediatrics, yet is a major cause of spontaneous intracranial hemorrhage with a risk of fatal hemorrhage reported to be between 4 ...

    Joshua Pepper, Saleh Lamin, Allan Thomas, A. Richard Walsh in Child's Nervous System (2023)

  5. No Access

    Article

    Molecular subgroup of medulloblastoma: evaluation of contribution to CSF diversion following tumour resection

    Medulloblastoma is the commonest malignant brain tumour in children. Pre-operative hydrocephalus is present in up to 90% of these patients at presentation. Following posterior fossa surgery, despite resolution...

    Fardad T. Afshari, Sebastian Toescu, Rehman Ali Baig, John Ong in Child's Nervous System (2023)

  6. No Access

    Article

    Spinal canal stenosis in children with achondroplasia: the role of augmentation laminoplasty—a 15-year single institution experience

    Achondroplasia typically results in compressive spinal canal stenosis in one-third of children, but rare under the age of 15 years. Laminectomy is the mainstay of treatment but this leads to instability and pr...

    Fardad T. Afshari, Naomi Slator, Oluwafikayo Fayeye in Child's Nervous System (2023)

  7. Article

    Myasthenia gravis complicating the surgical management of achondroplasia: a case-based update

    Achondroplasia is the commonest skeletal dysplasia of autosomal dominant inheritance caused by “gain of function” mutations in the fibroblast growth factor receptor 3 (FGFR3) gene. Foramen magnum compression d...

    Fardad T. Afshari, Amitav Parida, Phillip Debenham in Child's Nervous System (2022)

  8. No Access

    Article

    Posterior Calvarial Distraction in older paediatric population: single centre paediatric neurosurgery craniofacial unit outcomes

    Posterior calvarial distraction (PCD) is a safe and effective technique used to increase cranial vault volume and therefore reduce intracranial pressure in children with complex craniosynostosis. Optimal timin...

    Fardad T. Afshari, Pasquale Gallo, Guirish A. Solanki in Child's Nervous System (2022)

  9. No Access

    Article

    Paediatric developmental venous anomalies (DVAs): how often do they bleed and where?

    Developmental venous anomalies (DVAs) are anomalies of venous drainage and considered a low-flow malformation. Studies evaluating natural history and risk factors for intracranial haemorrhage in the paediatric...

    Adikarige H. D. Silva, Haren Wijesinghe, William B. Lo in Child's Nervous System (2020)

  10. No Access

    Article

    Paediatric spondylodiscitis: a 10-year single institution experience in management and clinical outcomes

    Discitis in the paediatric population poses diagnostic challenges due to non-specific presenting symptoms and difficulty with expressing pain in non-communicating children. Discitis remains a relatively rare c...

    Fardad T. Afshari, Desiderio Rodrigues, Mahesh Bhat in Child's Nervous System (2020)

  11. No Access

    Article

    Consent in paediatric neurosurgery: adequacy of documentation and parental perspectives

    Consenting paediatric patients for surgical procedures remains inherently unique in that it is underpinned by principles such as parental responsibility, assessment of the child’s capacity to consent, and adhe...

    Adikarige H. D. Silva, Haren Wijesinghe, Nilesh Mundil in Child's Nervous System (2019)

  12. No Access

    Article

    Paediatric intracranial aneurysms: a British institutional review

    Paediatric intracranial aneurysms are rare, with a differing natural history and thought to account for only up to 7% of all intracranial aneurysms. There is much uncertainty that surrounds the prevalence of u...

    Naomi Slator, Sayed Samed Talibi, Nilesh Mundil, Allan Thomas in Child's Nervous System (2019)

  13. Article

    Open Access

    Positional plagiocephaly following ventriculoperitoneal shunting in neonates and infancy—how serious is it?

    We test the hypothesis that ventriculoperitoneal (VP) shunt insertion significantly increases contralateral positional plagiocephaly.

    Stuart A. G. Roberts, Joseph D. Symonds, Reema Chawla, Emma Toman in Child's Nervous System (2017)

  14. No Access

    Chapter

    Developmental Anatomy

    Many cases of hindbrain hernia are due to developmental abnormalities of the skull and/or the craniocervical junction. In this chapter the development of the nervous system, skull, vertebrae and associated mes...

    Guirish A. Solanki in Syringomyelia (2014)

  15. Article

    Open Access

    MRI morphometric characterisation of the paediatric cervical spine and spinal cord in children with MPS IVA (Morquio-Brailsford syndrome)

    Nearly all children with MPS IVA develop skeletal deformities affecting the spine. At the atlanto-axial spine, odontoid hypoplasia occurs. GAG deposition around the dens, leads to peri-odontoid infiltration. T...

    Guirish A. Solanki, William B. Lo in Journal of Inherited Metabolic Disease (2013)

  16. Article

    Open Access

    Anaesthesia and airway management in mucopolysaccharidosis

    This paper provides a detailed overview and discussion of anaesthesia in patients with mucopolysaccharidosis (MPS), the evaluation of risk factors in these patients and their anaesthetic management, including ...

    Robert Walker, Kumar G. Belani in Journal of Inherited Metabolic Disease (2013)

  17. Article

    Open Access

    Spinal involvement in mucopolysaccharidosis IVA (Morquio-Brailsford or Morquio A syndrome): presentation, diagnosis and management

    Mucopolysaccharidosis IVA (MPS IVA), also known as Morquio-Brailsford or Morquio A syndrome, is a lysosomal storage disorder caused by a deficiency of the enzyme N-acetyl-galactosamine-6-sulphate sulphatase (GALN...

    Guirish A. Solanki, Kenneth W. Martin in Journal of Inherited Metabolic Disease (2013)

  18. No Access

    Article

    Paediatric lumbar disc herniation in the very young: A case-based update

    A lumbar disc prolapse is commonly seen in the adult population and as a result, the signs and symptoms are well recognised and easily treated. A disc prolapse, in the adolescent and particularly the paediatri...

    Julian Cahill, Geoffrey Frost, Guirish A. Solanki in Child's Nervous System (2011)

  19. No Access

    Article

    Clinical Significance of Medication Reconciliation in Children Admitted to a UK Pediatric Hospital

    In December 2007, the National Institute for Health and Clinical Excellence and the National Patient Safety Agency in the UK (NICE-NPSA) published guidance that recommends all adults admitted to hospital recei...

    Mr David R. P. Terry, Guirish A. Solanki, Anthony G. Sinclair in Pediatric Drugs (2010)

  20. No Access

    Article

    Multiple coexistent dysraphic pathologies

    Four distinct dysraphic anomalies were observed in a single child. While combinations of such anomalies are well recognised, quadruple dysraphic pathology, nevertheless, is extremely uncommon. To our knowledge...

    Guirish A. Solanki, James Evans, Andrew Copp in Child's Nervous System (2003)