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    Article

    CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer’s disease

    Alzheimer’s disease (AD) is the most common form of neurodegenerative disease featured with memory loss and cognitive function impairments. Chronic mitochondrial stress is a vital pathogenic factor for AD and ...

    Wenting **e, Dong Guo, Jieyin Li, Lei Yue, Qi Kang in Cell Death & Differentiation (2022)

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    Open Access

    Cyclin-dependent kinase 5-mediated phosphorylation of chloride intracellular channel 4 promotes oxidative stress-induced neuronal death

    Oxidative stress can cause apoptosis in neurons and may result in neurodegenerative diseases. However, the signaling mechanisms leading to oxidative stress–induced neuronal apoptosis are not fully understood. ...

    Dong Guo, Wenting **e, Pan **ong, Huifang Li, Siqi Wang in Cell Death & Disease (2018)