3 Result(s)
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Guimiao Chen
Life Sciences
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Article
Open AccessExpression of SHH signaling molecules in the develo** human primary dentition
Our current knowledge on tooth development derives primarily from studies in mice. Very little is known about gene expression and function during human odontogenesis. Sonic Hedgehog (SHH) signaling has been de...
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Article
Open AccessCyclin-dependent kinase 5-mediated phosphorylation of chloride intracellular channel 4 promotes oxidative stress-induced neuronal death
Oxidative stress can cause apoptosis in neurons and may result in neurodegenerative diseases. However, the signaling mechanisms leading to oxidative stress–induced neuronal apoptosis are not fully understood. ...
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Article
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer’s disease
Alzheimer’s disease (AD) is the most common form of neurodegenerative disease featured with memory loss and cognitive function impairments. Chronic mitochondrial stress is a vital pathogenic factor for AD and ...
