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  1. Article

    Open Access

    Altered cortical synaptic lipid signaling leads to intermediate phenotypes of mental disorders

    Excitation/inhibition (E/I) balance plays important roles in mental disorders. Bioactive phospholipids like lysophosphatidic acid (LPA) are synthesized by the enzyme autotaxin (ATX) at cortical synapses and mo...

    Oliver Tüscher, Muthuraman Muthuraman, Johann-Philipp Horstmann in Molecular Psychiatry (2024)

  2. Article

    Correction: Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders

    Following the publication of this article the authors noted that Torfi Sigurdsson’s name was misspelled. Instead of Sigrudsson it should be Sigurdsson. The PDF and HTML versions of the paper have been modified...

    Carine Thalman, Guilherme Horta, Lianyong Qiao, Heiko Endle in Molecular Psychiatry (2020)

  3. No Access

    Article

    Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders

    Carine Thalman, Guilherme Horta, Lianyong Qiao, Heiko Endle in Molecular Psychiatry (2018)

  4. Article

    Open Access

    Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders

    Lysophosphatidic acid (LPA) is a synaptic phospholipid, which regulates cortical excitation/inhibition (E/I) balance and controls sensory information processing in mice and man. Altered synaptic LPA signaling ...

    Carine Thalman, Guilherme Horta, Lianyong Qiao, Heiko Endle in Molecular Psychiatry (2018)