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Open AccessAltered cortical synaptic lipid signaling leads to intermediate phenotypes of mental disorders
Excitation/inhibition (E/I) balance plays important roles in mental disorders. Bioactive phospholipids like lysophosphatidic acid (LPA) are synthesized by the enzyme autotaxin (ATX) at cortical synapses and mo...
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AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids
Phospholipid levels are influenced by peripheral metabolism. Within the central nervous system, synaptic phospholipids regulate glutamatergic transmission and cortical excitability. Whether changes in peripher...
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Correction: Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders
Following the publication of this article the authors noted that Torfi Sigurdsson’s name was misspelled. Instead of Sigrudsson it should be Sigurdsson. The PDF and HTML versions of the paper have been modified...
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Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders
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Open AccessSynaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders
Lysophosphatidic acid (LPA) is a synaptic phospholipid, which regulates cortical excitation/inhibition (E/I) balance and controls sensory information processing in mice and man. Altered synaptic LPA signaling ...
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Open AccessNeurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception
Adult neural stem cells reside in a specialized niche in the subventricular zone (SVZ). Throughout life they give rise to adult-born neurons in the olfactory bulb (OB), thus contributing to neural plasticity a...
