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Open AccessEngineering nanoparticles-enabled tumor-associated macrophages repolarization and phagocytosis restoration for enhanced cancer immunotherapy
Tumor-associated macrophages (TAMs) are pivotal within the immunosuppressive tumor microenvironment (TME), and recently, have attracted intensive attention for cancer treatment. However, concurrently to promot...
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Article
Light-activated arginine-rich peptide-modified nanoparticles for deep-penetrating chemo-photo-immunotherapy of solid tumor
Poor permeation of drugs and “immune-cold” tumor microenvironment in solid tumors are the two major challenges which lead to the inefficient therapeutic efficacy for cancer treatment. Here, light-activated pen...
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Article
Open AccessResearch on action behavior of neuron system in case of single pulse stimulus
Facing on the complex electromagnetic environment of electrical equipment, based on the bio-anti-interference characteristics of neuron system, the bio-inspired electromagnetic protection is proposed in order ...
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Article
Doxorubicin-loaded micelles based on multiarm star-shaped PLGA–PEG block copolymers: influence of arm numbers on drug delivery
Star-shaped block copolymers based on poly(d,l-lactide-co-glycolide) (PLGA) and poly(ethylene glycol) (PEG) (st-PLGA–PEG) were synthesized with structural variation on arm numbers in order to investigate the rela...
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Article
Synthesis and characterization of star-shaped poly (lactide-co-glycolide) and its drug-loaded microspheres
The star-shaped poly (lactide-co-glycolide) (PLGA) was synthesized via the ring-opening polymerization of d,l-lactide and glycolide, with pentaerythritol as a multifunctional initiator and stannous 2-ethyl hexano...
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Article
Preparation and characterization of the molecular weight controllable poly(lactide-co-glycolide)
A series of poly(d,l-lactide-co-glycolide) (PLGA) polymers with various molecular weight were synthesized by a ring-opening polymerization method using stannous 2-ethyl hexanoate (Sn(Oct)2) as the catalyst. The m...