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Article
Open AccessSCG5 and MITF may be novel markers of copper metabolism immunorelevance in Alzheimer’s disease
The slow-develo** neurological disorder Alzheimer’s disease (AD) has no recognized etiology. A bioinformatics investigation verified copper metabolism indicators for AD development. GEO contributed AD-relate...
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Article
Open AccessAn immune-related adverse event of Behcet’s-like syndrome following pembrolizumab treatment
In recent years, the emergence of immunotherapy has renewed therapeutic modality. Different from traditional anti-tumor therapy, immune-related adverse events of skin, gastrointestinal tract, liver, lung, endo...
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Article
Flexible 2D S-CNF/Au NSs substrate for detection of malondialdehyde in serum of gastric cancer patients
A two-dimensional (2D) substrate composed of nanocellulose-gold nanostars (S-CNF/Au NSs) was prepared, which exhibited remarkable homogeneity and stability. P-aminothiophenol (PATP) was modified on the S-CNF/A...
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Article
Open AccessMulti-omics reveals the role of ENO1 in bladder cancer and constructs an epithelial-related prognostic model to predict prognosis and efficacy
α-Enolase (ENO1) is a crucial molecular target for tumor therapy and has emerged as a research hotspot in recent decades. Here, we aimed to explore the role of ENO1 in bladder cancer (BLCA) and then construct a s...
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Article
Fabricating Surface Composite by Friction Stir Brazing SiCp/A356 Composite Sheet onto Monolithic Al Plate in Air
For improving the wear resistance of soft Al substrate by fabricating surface composite, commercial Al metal matrix composite (MMC) SiCp/A356 sheet was cladded onto 1060 Al substrate by friction stir brazing (FSB...
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Article
Preparation of SERS base membrane with cellulose compound dopamine and determination of hypochlorite
Flexible silver substrates were made by in situ reduction of silver nanoparticles in bacterial cellulose membranes using the unique advantage of dopamine. Subsequently, we modified the substrate with 4-mercapt...
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Article
Open AccessEfficacy and safety of fluzoparib combined with anlotinib in extensive stage small cell lung cancer after first-line platinum-based chemotherapy: a multi-center, single-arm prospective phase II clinical study (STAMP study)
Small-cell lung cancer (SCLC) is a highly aggressive and lethal malignancy that accounts for 10–15% of lung cancers, and it is generally divided into limited and extensive stage. The standard of care for patie...
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Chapter and Conference Paper
A Review of Client Selection Mechanisms in Heterogeneous Federated Learning
Federated learning is a distributed machine learning approach that keeps data locally while achieving the utilization of fragmented data and protecting client privacy to a certain extent. However, the existenc...
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Article
NUDT15 genetic testing-guided 6-mercaptopurine dosing in children with ALL likely to be cost-saving in China
The cost-effectiveness of NUDT15 genetic testing-guided initial 6-mercaptopurine (6-MP) dosing in children with acute lymphoblastic leukemia (ALL) was evaluated.
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Chapter and Conference Paper
A Screening Method for Dangerous Models of 3D Printed Bionic Artificial Vertebral Bodies - Finite Element Analysis
Spinal tumors can occur in or around the spine and may cause defects in the anterior column of the vertebral body, spinal instability, nerve and spinal cord damage, and other symptoms. Benefiting from the rapi...
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Article
Cost-effectiveness Analysis of CYP2D6*10 Pharmacogenetic Testing to Guide the Adjuvant Endocrine Therapy for Postmenopausal Women with Estrogen Receptor Positive Early Breast Cancer in China
A CYP2D6 gene polymorphism is related to the effect of tamoxifen treatment in patient with estrogen-receptor positive (ER) positive breast cancer and CYP2D6*10 T/T can lead to a poor prognosis in Asian patients. ...
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Article
Effect of Zn and mechanical vibration agitation on the microstructure evolution in brazed joint of SiC particle-reinforced aluminum matrix composites
In order to broaden SiC particle-reinforced aluminum matrix composites in the applications of high-temperature and high-power electronic devices for electronics packaging, three types of the zinc-containing fi...
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Article
Application of AlMgGaLi foil for joining copper to SiCp/Al-MMCs for high-temperature and high-power electronics
A novel lead-free foil (AlMgGaLi) with a melting point of 398.3 ~ 414.8 °C was developed for active soldering of copper to aluminum matrix composite. The effect of joining pressure on the microstructure, inter...
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Article
Dissimilar Joining of Pure Aluminum to SiCp/Al-MMCs Using an AlMgGaLi Active Interlayer Foil
To broaden the application of advanced metal matrix composites in the electronic packaging industry, a lead-free AlMgGaLi interlayer was developed for active soldering of aluminum to aluminum metal matrix comp...
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Article
Grain-Refined Microstructure and Hard Surface Layer Produced by SMRGT Process for Improved Corrosion Behavior of Mg-3Al-1Zn Alloy
To improve the surface properties and performance, a grain-refined surface layer was produced on AZ31B Mg alloy by a newly developed surface nano-crystallization and hardening process called surface mechanical...
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Chapter and Conference Paper
Fog Concentration Grade Judgment for Meter Reading Based on SVM
Robot reading energy meter devices automatically is a basic task for smart grid. Unfortunately, the predicted accuracy is influenced by environment dramatically. In order to solve the problem, we propose a met...
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Chapter and Conference Paper
Meter Detection of Substation Scene Based on Deep Learning
Automatic detection of the substation meters based on deep learning is of great importance. Meters are important equipment for monitoring substations safety. A large number of meters in the substation need to...
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Article
A new approach of a gradient nanograined surface layer for Mg-3Al-1Zn alloy induced by SMRGT
In order to improve the overall properties and performance, a gradient nanostructured surface layer on AZ31B magnesium alloy was generated by newly developed surface nanocrystallization (SNC) and hardening pro...
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Article
Abnormal Transient Liquid Phase Bondability of High-Volume Fraction SiC Particle-Reinforced A356 Composite for Cu Interlayer and the Interlayer Improvement Routes
Features of transient liquid phase (TLP) bondability of high-volume fraction (70 vol.%) SiC particle-reinforced A356 composite for popular Cu interlayer were investigated. Although Cu foil was melted, molten C...
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Article
High-Temperature Active Soldering of SiC Particle-Reinforced Al-MMC Using a Novel ZnAlGaMgTi Filler Metal
In order to broaden the application of SiC particle-reinforced aluminum matrix composite in electronics packaging, newly developed ZnAlGaMgTi filler with a low melting point of 418-441 °C was utilized as fille...
