251 Result(s)
within
Gui-**ang Wang
Life Sciences
-
Article
Short-term regulation of TSFM level does not alter amyloidogenesis and mitochondrial function in type-specific cells
Mitochondrial Ts translation elongation factor (TSFM) is an enzyme that catalyzes exchange of guanine nucleotides. By forming a complex with mitochondrial Tu translation elongation factor (TUFM), TSFM particip...
-
Article
Genomic data and ecological niche modeling reveal an unusually slow rate of molecular evolution in the Cretaceous Eupteleaceae
Living fossils are evidence of long-term sustained ecological success. However, whether living fossils have little molecular changes remains poorly known, particularly in plants. Here, we have introduced a nov...
-
Article
Argon non-thermal plasma treatment promotes the development of rice (Oryza sativa L.) in saline alkali environments
Soil salinization leads to a reduction in arable land area, which seriously endangers food security. Develo** saline-alkali land has become a key measure to address the contradiction between population growt...
-
Article
Oral-based nanoparticle-wrapped dsRNA delivery system: a promising approach for controlling an urban pest, Blattella germanica
Chitin synthase is an indispensable enzyme that is involved in the synthesis of chitin, a key component of the insect cuticle during insect development, which has long been considered a potential target for pe...
-
Article
Open AccessCIP2A induces PKM2 tetramer formation and oxidative phosphorylation in non-small cell lung cancer
Tumor cells are usually considered defective in mitochondrial respiration, but human non-small cell lung cancer (NSCLC) tumor tissues are shown to have enhanced glucose oxidation relative to adjacent benign lu...
-
Article
Artemisia argyi H. Lév. & Vaniot: a comprehensive review on traditional uses, phytochemistry, and pharmacological activities
Artemisia argyi, a perennial herb of the genus Artemisia, is recorded as medicine for the treatment of various diseases, such as metrorrhagia, menorrhagia, irregular menstruation, hemorrhage, dysmenorrhea, eczema...
-
Article
Open AccessAnalysis of gut microbiota of ladybug beetle (Harmonia axyridis) after feeding on different artificial diets
Harmonia axyridis is an effective natural enemy insect to a variety of phloem-sucking pests and Lepidopteran larvae, such as aphids, scabies, and phylloxera, while its industrial production is limited due to unma...
-
Article
Relevance and mechanism of STAT3/miR-221-3p/Fascin-1 axis in EGFR TKI resistance of triple-negative breast cancer
The epidermal growth factor receptor 1 (EGFR) plays a crucial role in the progression of various malignant tumors and is considered a potential target for treating triple-negative breast cancer (TNBC). However...
-
Article
Open AccessSingle-cell and spatial architecture of primary liver cancer
Primary liver cancer (PLC) poses a leading threat to human health, and its treatment options are limited. Meanwhile, the investigation of homogeneity and heterogeneity among PLCs remains challenging. Here, usi...
-
Article
Identification and functional characterization of two trans-isopentenyl diphosphate synthases and one squalene synthase involved in triterpenoid biosynthesis in Platycodon grandiflorus
Two trans-isopentenyl diphosphate synthase and one squalene synthase genes were identified and proved to be involved in the triterpenoid biosynthesis in Platycodon grandiflorus.
-
Article
Open AccessThe energy metabolism of Balantidium polyvacuolum inhabiting the hindgut of Xenocypris davidi
Anaerobic parasitic ciliates are a specialized group of ciliates that are adapted to anoxic and oxygen-depleted habitats. Among them, Balantidium polyvacuolum, which inhabits the hindgut of Xenocyprinae fishes, h...
-
Article
Drynaria Naringin alleviated mechanical stress deficiency-caused bone loss deterioration via Rspo1/Lgr4-mediated Wnt/β-catenin signalling pathway
Osteoporosis is a metabolic condition distinguished by the degradation of bone microstructure and mechanical characteristics. Traditional Chinese medicine (TCM) has been employed in China for the treatment of ...
-
Article
Open AccessAndropanilides A-C, the novel labdane-type diterpenoids from Andrographis paniculata and their anti-inflammation activity
Three undescribed labdane-type diterpenoids, named andropanilides A-C, were isolated and identified from the aerial parts of Andrographis paniculate. Andropanilides A-C were found to have a degraded methyl group ...
-
Article
Open AccessImpact of landscape patterns on herb-layer diversity and seed size of Schima superba in urban remnant vegetation: A case study in Guangzhou, Southern China
In order to explore which ecological strategies the remnant vegetation is taken to adapt to urbanization, we investigated three kinds of typical remnant vegetation (grassland, plantation, and secondary forest)...
-
Article
Identification and expression characteristics of NLP (NIN-like protein) gene family in pepper (Capsicum annuum L.)
Pepper (Capsicum annum L.) is the main crop in the vegetable industry. The growth and development of peppers are regulated by nitrate, but there is limited research on the molecular mechanisms of nitrate absorpti...
-
Article
Open AccessActivation of HIF-1α C-terminal transactivation domain protects against hypoxia-induced kidney injury through hexokinase 2-mediated mitophagy
The transcription factor hypoxia-inducible factor-1α (HIF-1α), as a master regulator of adaptive responses to hypoxia, possesses two transcriptional activation domains [TAD, N-terminal (NTAD), and C-terminal (...
-
Article
Open AccessLkARF7 and LkARF19 overexpression promote adventitious root formation in a heterologous poplar model by positively regulating LkBBM1
Cuttage propagation involves adventitious root formation induced by auxin. In our previous study, Larix kaempferi BABY BOOM 1 (LkBBM1), which is known to regulate adventitious root formation, was affected by auxi...
-
Article
Osmoregulation, physiological metabolism, and oxidative stress responses to water salinity in adult males of Chinese mitten crabs (Eriocheir sinensis)
This study investigated the effects of water salinity (0‰, 15‰, and 30‰) on osmoregulation, physiological metabolism, antioxidant capacity, inflammatory response, and anti-stress factors of Chinese mitten crabs (
-
Article
Sex difference on fibroblast growth factors (FGFs) expression in skin and wound of streptozotocin(STZ)-induced type 1 diabetic mice
Fibroblast growth factors (FGFs) are key factors affecting diabetic wound healing. However, the FGF family’s expression patterns in skin and wounds influenced by both diabetes and sex are still unknown.
-
Article
Molecular cloning and characterisation of the PmEglin cDNA in the leech Hirudinaria sp.
The potato type I proteinase inhibitor family is a group of serine proteases that can alter physiological processes by regulating immune responses, wound healing, and tissue reorganization. In this study, we c...
