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  1. No Access

    Article

    Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

    Rho guanine nucleotide dissociation inhibitors (RhoGDIs) bind to inactive Rho GTPases in the cytosol, but their function remains unclear. Several Rho GTPases are now shown to compete for RhoGDI binding and thi...

    Etienne Boulter, Rafael Garcia-Mata, Christophe Guilluy, Adi Dubash… in Nature Cell Biology (2010)

  2. No Access

    Article

    Bet2p and Mad2p are components of a prenyltransferase that adds geranylgeranyl onto Ypt1p and Sec4p

    THREE different prenyltransferases have been identified in yeast and higher cells1–6, the farnesyltransferase and the type I and type II geranylgeranyltransferases (GGTase). The farnesyltransferase and GGTase-I m...

    Yu Jiang, Guendalina Rossi, Susan Ferro-Novick in Nature (1993)

  3. No Access

    Article

    Dependence of Ypt1 and Sec4 membrane attachment on Bet2

    MANY small GTP-binding proteins are synthesized as soluble proteins that are post-translationally modified as a prerequisite for membrane attachment1. Ypt1 and Sec4 are homologous Ras-like GTP-binding proteins th...

    Guendalina Rossi, Yu Jiang, Anna P. Newman, Susan Ferro-Novick in Nature (1991)