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Open AccessAgreement and repeatability of scotopic pupil size measurement with the 2WIN-S portable refractor in Chinese adults
To assess the agreement and repeatability of scotopic pupil size measurement using 2WIN-S (Adaptica, Padova, Italy) portable refractor in Chinese adults. This prospective non-randomized open-label controlled ...
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Article
Open AccessValidity of OSDI-6 questionnaire in a Chinese adult population
This study aimed to evaluate the validity of the Chinese translation version of OSDI-6 (C-OSDI-6) using a virtual set-up questionnaire for dry eye disease. A total of 270 participants (136 males, 50.4% and 134...
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Article
Open AccessTrends in chlamydia prevalence in the United States, 2005–2016
In the United States (US), chlamydia is the most frequently reported sexually transmitted infection that is nationally notifiable. We examined trends in chlamydia prevalence in the US in 2011–2016 compared wit...
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Article
Open AccessEvaluation of recoverable potential of deep coalbed methane in the Linxing Block, Eastern Margin of the Ordos Basin
The deep coalbed methane (CBM) resources are widely developed in the Linxing Block. However, the evaluation of CBM geological areas suitable for CBM exploitation remains unexplored, hindering further developme...
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Open AccessA membrane associated tandem kinase from wild emmer wheat confers broad-spectrum resistance to powdery mildew
Crop wild relatives offer natural variations of disease resistance for crop improvement. Here, we report the isolation of broad-spectrum powdery mildew resistance gene Pm36, originated from wild emmer wheat, that...
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Open AccessDevelopment of machine learning-based predictors for early diagnosis of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) remains a formidable malignancy that significantly impacts human health, and the early diagnosis of HCC holds paramount importance. Therefore, it is imperative to develop an effi...
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Open AccessLinear and phase controllable terahertz frequency conversion via ultrafast breaking the bond of a meta-molecule
The metasurface platform with time-varying characteristics has emerged as a promising avenue for exploring exotic physics associated with Floquet materials and for designing photonic devices like linear freque...
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Article
Open AccessAccelerating thermokarst lake changes on the Qinghai–Tibetan Plateau
As significant evidence of ice-rich permafrost degradation due to climate warming, thermokarst lake was develo** and undergoing substantial changes. Thermokarst lake was an essential ecosystem component, whi...
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Article
Open AccessIdentification and validation of novel prognostic signatures based on m5C methylation patterns and tumor EMT profiles in head and neck squamous cell carcinoma
The role of 5-methylcytosine (m5C) in tumor initiation and progression has been increasingly recognized. However, the precise association between the regulation of m5C and the progression, metastasis, and prog...
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Article
Open AccessSingle-cell allele-specific expression analysis reveals dynamic and cell-type-specific regulatory effects
Differential allele-specific expression (ASE) is a powerful tool to study context-specific cis-regulation of gene expression. Such effects can reflect the interaction between genetic or epigenetic factors and ...
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Article
Open AccessTargeting C/EBPα overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia
The outcomes of FLT3-ITD acute myeloid leukaemia (AML) have been improved since the approval of FLT3 inhibitors (FLT3i). However, approximately 30-50% of patients exhibit primary resistance (PR) to FLT3i with poo...
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Open AccessVertically optimized phase separation with improved exciton diffusion enables efficient organic solar cells with thick active layers
The development of organic solar cells (OSCs) with thick active layers is of crucial importance for the roll-to-roll printing of large-area solar panels. Unfortunately, increasing the active layer thickness us...
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Article
Open AccessMicrofluidic manipulation by spiral hollow-fibre actuators
A microfluidic manipulation system that can sense a liquid and control its flow is highly desirable. However, conventional sensors and motors have difficulty fitting the limited space in microfluidic devices; ...
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Open AccessAn integrated pore size distribution measurement method of small angle neutron scattering and mercury intrusion capillary pressure
Small-angle neutron scattering and high-pressure mercury intrusion capillary pressure testing are integrated to analyze the pore size distribution of the broad sense shale oil reservoir samples of the Permian ...
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Article
Open AccessChild-directed speech is optimized for syntax-free semantic inference
The way infants learn language is a highly complex adaptive behavior. This behavior chiefly relies on the ability to extract information from the speech they hear and combine it with information from the exter...
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Open AccessOptimized active layer morphology toward efficient and polymer batch insensitive organic solar cells
Morphology control in laboratory and industry setting remains as a major challenge for organic solar cells (OSCs) due to the difference in film-drying kinetics between spin coating and the printing process. A ...
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Open AccessA rare gain of function mutation in a wheat tandem kinase confers resistance to powdery mildew
Powdery mildew, caused by Blumeria graminis f. sp. tritici (Bgt), is one of the most destructive diseases that pose a great threat to wheat production. Wheat landraces represent a rich source of powdery mildew re...
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Article
Open AccessMendelian randomization analysis using mixture models for robust and efficient estimation of causal effects
Mendelian randomization (MR) has emerged as a major tool for the investigation of causal relationship among traits, utilizing results from large-scale genome-wide association studies. Bias due to horizontal pl...
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Article
Open AccessSynergic effect of adsorbed gas and charging on surface flashover
Flashover is a crucial issue in both high-voltage engineering and surface physics. It not only challenges the existing theories about its dynamic evolution, but also inhibits the clean energy revolution by lim...
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Open AccessPublisher Correction: Trap** and manipulation of nanoparticles using multifocal optical vortex metalens
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.