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  1. No Access

    Article

    Non-complementary computation

    Molecular computing programmed with complementary nucleic acid strands allows the construction of sophisticated biomolecular circuits. Now, systems with partially complementary strands have been shown to enabl...

    Philip Petersen, Grigory Tikhomirov in Nature Chemistry (2023)

  2. Chapter

    Beyond DNA: New Digital Polymers

    From a programming perspective, DNA is stunningly simple: a string of bits coding two types of interactions. The specific chemical form of DNA given to us by evolution imposes significant constraints on what is p...

    Grigory Tikhomirov in Visions of DNA Nanotechnology at 40 for the Next 40 (2023)

  3. Article

    Open Access

    Author Correction: Information-based autonomous reconfiguration in systems of interacting DNA nanostructures

    The original version of this Article omitted a reference to previous work in ‘Stojanovic, M. N. & Stefanovic, D. A deoxyribozyme-based molecular automaton. Nat. Biotechnol. 21, 1069–1074 (2003)’. This has been ad...

    Philip Petersen, Grigory Tikhomirov, Lulu Qian in Nature Communications (2019)

  4. Article

    Open Access

    Information-based autonomous reconfiguration in systems of interacting DNA nanostructures

    The dynamic interactions between complex molecular structures underlie a wide range of sophisticated behaviors in biological systems. In building artificial molecular machines out of DNA, an outstanding challe...

    Philip Petersen, Grigory Tikhomirov, Lulu Qian in Nature Communications (2018)

  5. No Access

    Article

    Fractal assembly of micrometre-scale DNA origami arrays with arbitrary patterns

    Simple assembly rules applied recursively in a multistage assembly process enable the creation of DNA origami arrays with sizes of up to 0.5 square micrometres and with arbitrary patterns.

    Grigory Tikhomirov, Philip Petersen, Lulu Qian in Nature (2017)

  6. No Access

    Article

    Programmable disorder in random DNA tilings

    Scaling up the complexity and diversity of synthetic molecular structures will require strategies that exploit the inherent stochasticity of molecular systems in a controlled fashion. Here we demonstrate a fra...

    Grigory Tikhomirov, Philip Petersen, Lulu Qian in Nature Nanotechnology (2017)

  7. No Access

    Article

    Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

    Directed self-assembly of small molecules in living systems could enable a myriad of applications in biology and medicine, and already this has been used widely to synthesize supramolecules and nano/microstruc...

    Deju Ye, Adam J. Shuhendler, Lina Cui, Ling Tong, Sui Seng Tee in Nature Chemistry (2014)

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    Article

    DNA-based programming of quantum dot valency, self-assembly and luminescence

    The electronic and optical properties of colloidal quantum dots, including the wavelengths of light that they can absorb and emit, depend on the size of the quantum dots. These properties have been exploited i...

    Grigory Tikhomirov, Sjoerd Hoogland, P. E. Lee, Armin Fischer in Nature Nanotechnology (2011)

  9. No Access

    Article

    Combinatorial Approach to Materials Fabrication from Higher Hierarchies of Rosette Nanotubes

    The self-assembly of six self-complimentary Guanine – Cytosine hybrid heterocycles bearing hydrophobic substituents has been studied using combinatorial approach in eight solvents under different conditions. T...

    Grigory Tikhomirov, Hicham Fenniri in MRS Online Proceedings Library (2008)