6 Result(s)
within
Gorka Alkorta-Aranburu
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Article
Open AccessBuilding on the clinical applicability of ctDNA analysis in non-metastatic pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma represents one of the solid tumors showing the worst prognosis worldwide, with a high recurrence rate after adjuvant or neoadjuvant therapy. Circulating tumor DNA analysis rais...
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Article
Open AccessGut microbiota produces biofilm-associated amyloids with potential for neurodegeneration
Age-related neurodegenerative diseases involving amyloid aggregation remain one of the biggest challenges of modern medicine. Alterations in the gastrointestinal microbiome play an active role in the aetiology...
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Article
Reprogramming human T cell function and specificity with non-viral genome targeting
Decades of work have aimed to genetically reprogram T cells for therapeutic purposes1,2 using recombinant viral vectors, which do not target transgenes to specific genomic sites3,4. The need for viral vectors has...
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Article
Admixture facilitates genetic adaptations to high altitude in Tibet
Admixture is recognized as a widespread feature of human populations, renewing interest in the possibility that genetic exchange can facilitate adaptations to new environments. Studies of Tibetans revealed can...
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Article
Correction: Corrigendum: Reconstructing Native American population history
Nature 488, 370–374 (2012); doi:10.1038/nature11258 At the time of publication of this Letter, the authors were unaware of a manuscript arriving at broadly similar conclusions based on allotype analysis by Wil...
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Reconstructing Native American population history
A survey of genetic variation in Native American and Siberian populations reveals that Native Americans are descended from at least three streams of gene flow from Asia: after the initial peopling of the conti...
