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Article
CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation
Gastrointestinal infections are a major cause for serious clinical complications in infants. The induction of antibody responses by B cells is critical for protective immunity against infections and requires C...
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Article
A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44
Natural killer (NK) cells can recognize virus-infected and stressed cells1 using activating and inhibitory receptors, many of which interact with HLA class I. Although early studies also suggested a functional im...
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Article
Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1
The activating NK cell receptor KIR3DS1 has been linked to the outcome of various human diseases, yet a ligand that would account for its biological effects has remained unknown. Altfeld and colleagues establi...