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Article
Open AccessQuantitative transport map** of multi-delay arterial spin labeling MRI detects early blood perfusion alterations in Alzheimer’s disease
Quantitative transport map** (QTM) of blood velocity, based on the transport equation has been demonstrated higher accuracy and sensitivity of perfusion quantification than the traditional Kety’s method-base...
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Article
Open Access[1-11C]-Butanol Positron Emission Tomography reveals an impaired brain to nasal turbinates pathway in aging amyloid positive subjects
Reduced clearance of cerebrospinal fluid (CSF) has been suggested as a pathological feature of Alzheimer’s disease (AD). With extensive documentation in non-human mammals and contradictory human neuroimaging d...
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Article
Open AccessPeripheral immune cell imbalance is associated with cortical beta-amyloid deposition and longitudinal cognitive decline
Neuroinflammation is believed to be a key process in Alzheimer’s disease (AD) pathogenesis. Recently, the neutrophil-to-lymphocyte (NLR) and lymphocyte-to-monocyte ratios (LMR) have been proposed to be useful ...
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Logopenic Variant Primary Progressive Aphasia
Logopenic variant primary progressive aphasia, one of the three clinical variants of primary progressive aphasia, differs from other variants because it is typically associated with underlying Alzheimer’s dise...
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Creutzfeldt-Jakob Disease
Creutzfeldt-Jakob disease (CJD) is a rare, fatal disease caused by prions, with rapidly progressive dementia leading to death in most patients within a year of clinical onset.
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Dementia with Lewy Bodies
Dementia with Lewy bodies is a progressive neurodegenerative α-synucleinopathy and the third most common cause of dementia, after Alzheimer’s disease and vascular dementia. Early diagnosis is useful for progno...
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Behavioral Variant Frontotemporal Dementia
Behavioral variant frontotemporal dementia (bvFTD) is among the most common types of nonvascular dementia and is as prevalent as Alzheimer’s disease (AD) among individuals with early-onset dementia. Due to its...
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Normal Pressure Hydrocephalus
Idiopathic normal pressure hydrocephalus (iNPH) is one of the few reversible causes of cognitive impairment, and many patients can be effectively treated with surgical placement of a ventricular shunt. The cli...
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The Role of Advanced Imaging in the Management of Brain Metastases
Imaging plays a major role in the management of brain metastases, both to diagnose metastases in the pretreatment period and to differentiate recurrent metastasis from radiation change in the posttreatment per...