10 Result(s)
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Giuseppina Barsacchi
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Article
Open AccessDorsoventral patterning of the Xenopus eye involves differential temporal changes in the response of optic stalk and retinal progenitors to Hh signalling
Hedgehog (Hh) signals are instrumental to the dorsoventral patterning of the vertebrate eye, promoting optic stalk and ventral retinal fates and repressing dorsal retinal identity. There has been limited analy...
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Genes, Evolution and the Development of the Embryo
Evolutionary Developmental Biology (Evo-Devo) deals with the relationships between the individual development and the phenotypic changes of the organism during evolution. Major morphological transitions in evo...
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Article
Open AccessA specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina
Otx genes, orthologues of the Drosophila orthodenticle gene (otd), play crucial roles in vertebrate brain development. In the Xenopus eye, Xotx2 and Xotx5b promote bipolar and photoreceptor cell fates, respective...
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Article
Cloning and developmental expression of the Xenopus homeobox gene Xvsx1
In contrast to the high degree of evolutionary conservation of the Vsx2/Chx10 gene family, vertebrate orthologues of Vsx1 display more divergent sequences and spatio-temporal expression patterns. Here, we report ...
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Organizing the Eye
“The complex apparatus of the vertebrate eye originates by a sequence of developmental processes which......are interlocked spatially and temporally”. So wrote Hans Spemann in 1901 (see Hamburger 1988, p. 18),...
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Article
Two dispersed highly repeated DNA families of Triturus vulgaris meridionalis (Amphibia, Urodela) are widely conserved among Salamandridae
Two BamHI families of repeated sequences were characterized from the genome of the Italian smooth newt, Triturus vulgaris meridionalis (Amphibia, Urodela). The first family, which is divided into subfamilies, con...
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Article
Heterochromatic DNA in Triturus (Amphibia, Urodela)
The MspI family of highly repeated sequences is a centromeric satellite DNA representing about 1% of the genome of the Italian smooth newt, Triturus vulgaris meridionalis. We have studied the structure, genomic o...
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Evolution of highly repeated DNA within the genusTriturus (Amphibia, Urodela)
Highly repeated DNA is a main feature of urodele amphibian genomes. InTriturus this class of DNA consists of several sequence families differently arranged at both the molecular and the chromosomal level, showing...
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The maps of the lampbrush chromosomes of Triturus (Amphibia urodela)
The lampbrush chromosomes of Triturus vulgaris meridionalis were isolated from the germinal vesicle of medium and large-sized oocytes and studied with phase-contrast microscope. The maps were constructed on the b...
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Article
The lampbrush chromosomes of Salamandra salamandra (L.) (Amphibia Urodela)
Lampbrush chromosomes isolated from the germinal vesicle of medium sized oocytes can be individually identified by differences in two characters: (1) chromosome regions rich in well developed loops, and (2) nu...
