3 Result(s)
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Giuseppe Del Giudice
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessExpression of the Streptococcus pneumoniae pilus-1 undergoes on and off switching during colonization in mice
Streptococcus pneumoniae pili contribute to adherence and virulence. The regulation of pilus-1 expression is bistable, thus piliated strains contain a variable proportion of pilus-1-non-expressing bacteria. We in...
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Article
Open AccessPlatformTM, a standards-based data custodianship platform for translational medicine research
Biomedical informatics has traditionally adopted a linear view of the informatics process (collect, store and analyse) in translational medicine (TM) studies; focusing primarily on the challenges in data integ...
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Article
Open AccessCharacterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium
Biomarkers predictive of inflammatory events post-vaccination could accelerate vaccine development. Within the BIOVACSAFE framework, we conducted three identically designed, placebo-controlled inpatient/outpat...
