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Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease

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    Ibuprofen Suppresses Interleukin-1β Induction of Pro-Amyloidogenic α1-Antichymotrypsin to Ameliorate β-Amyloid (Aβ) Pathology in Alzheimer's Models

    Epidemiological and basic research suggests that nonsteroidal anti-inflammatory drugs (NSAIDs) should protect against the most common forms of Alzheimer's disease (AD). Ibuprofen reduces amyloid (Aβ) pathology in...

    Takashi Morihara, Bruce Teter, Fusheng Yang, Giselle P Lim… in Neuropsychopharmacology (2005)

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