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Article
Open AccessCirculating Osteopontin Predicts Clinical and Radiological Response in First-Line Treatment of Advanced Non-Small Cell Lung Cancer
Pembrolizumab-based regimens are conditioned by the expression of PD-L1, but durable response rate is limited by innate and acquired resistance mechanisms. Here, we focus on osteopontin (OPN), an upfront bioma...
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Article
Open AccessA functional role of Ephrin type-B receptor 6 (EPHB6) in T-cell acute lymphoblastic leukemia
T-cell lymphoblastic acute leukemia (T-ALL) is an aggressive blood cancer, characterized by restricted cellular subsets with enriched leukemia initiating cells (LICs). Recently, Ephrin receptors (Eph) were des...
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Article
Open AccessCorrection: Mitochondrial phylogeny and taxonomic revision of Italian and slovenian fluvio-lacustrine barbels, Barbus sp. (Cypriniformes, Cyprinidae)
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Article
Open AccessShared cross-cultural principles underlie human prosocial behavior at the smallest scale
Prosociality and cooperation are key to what makes us human. But different cultural norms can shape our evolved capacities for interaction, leading to differences in social relations. How people share resource...
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Chapter and Conference Paper
Multiple Regression Model to Analyze the Length of Stay for Patients Undergoing Laparoscopic Appendectomy: A Bicentric Study
Cost-containment and efficiency are aspects that have more and more weight in the evaluation of the performance of healthcare facilities. This trend, coupled with the ever-rising complexity of the services and...
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Chapter and Conference Paper
Modeling LOS After Percutaneous Valvuloplasty: A Bicentric Study
Pathologies involving the heart valves lead to alterations that can be restrictive (valve stenosis) or incontinence (valve insufficiency). Valvular heart disease led often to make surgery, in the case of the s...
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Chapter and Conference Paper
Predictive Algorithms to Study the Hospitalization for Knee Replacement Surgery: A Bicentric Study
Knee replacement surgery is one of the most interesting procedures in surgery. Patients generally have an LOS of about 5 days and when it increases it is related to clinical factors and the patient’s comorbidi...
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Chapter and Conference Paper
Covid-19: The Effect on Hospitalization Patient of Ophthalmology Department in “Antonio Cardarelli” Hospital
A pneumonia outbreak of unknown origin was reported in Wuhan, China in late December. This virus, called coronavirus-2
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Chapter and Conference Paper
Analysis of Hospital Admissions of Neurological Patients in the COVID-19 Era: Comparison Between Hospitals
In the last few years, the COVID-19 pandemic has strongly affected different hospital departments, revealing their major weaknesses. For this reason, this emergency has been a driver for healthcare transformat...
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Chapter and Conference Paper
Use of Statistical Analysis to Evaluate How Covid-19 Has Changed the Management of the Neurosurgery Department of the AORN “A. Cardarelli” in Naples
The pandemic related to the Covid-19 virus that began in 2019 in China and then extended to the rest of the world has led to changes in the management of almost all clinical specializations. The main adaptatio...
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Chapter and Conference Paper
Impact of COVID-19 in a Surgery Department: Comparison Between Two Italian Hospitals
The main phenomenon that impacted people’s lives was the COVID-19 pandemic, having strong consequences on national health systems. Since the beginning of the Covid-19 pandemic, hospital admissions dropped prec...
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Article
Open AccessExtracellular vesicle microRNAs contribute to Notch signaling pathway in T-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive T-cell malignancy characterized by genotypically-defined and phenotypically divergent cell populations, governed by adaptive landscapes. Clonal expa...
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Article
Open AccessPrognostic value of immunotherapy-induced organ inflammation assessed on 18FDG PET in patients with metastatic non-small cell lung cancer
We evaluated the prognostic value of immunotherapy-induced organ inflammation observed on 18FDG PET in patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICPIs).
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Article
Open AccessMultiple regression model to analyze the total LOS for patients undergoing laparoscopic appendectomy
The rapid growth in the complexity of services and stringent quality requirements present a challenge to all healthcare facilities, especially from an economic perspective. The goal is to implement different s...
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Article
Open AccessMitochondrial phylogeny and taxonomic revision of Italian and Slovenian fluvio-lacustrine barbels, Barbus sp. (Cypriniformes, Cyprinidae)
Barbels are ray finned cyprinid fishes of the Old-World with partially unresolved, intricate taxonomy. Within the Barbus sensu lato paraphyletic assemblage, Barbus sensu stricto is a monophyletic tetraploid linea...
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Article
Open AccessCPX-351 treatment in secondary acute myeloblastic leukemia is effective and improves the feasibility of allogeneic stem cell transplantation: results of the Italian compassionate use program
Secondary acute myeloid leukemia (sAML) poorly responds to conventional treatments and allogeneic stem cell transplantation (HSCT). We evaluated toxicity and efficacy of CPX-351 in 71 elderly patients (median ...
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Article
RETRACTED ARTICLE: Can baseline endocrinological examination and thyroid ultrasound predict the development of thyroid disease in immunotherapy-treated patients? Results from a prospective, single-center, open-label study
The authors are retracting this article [1] because they do not have permission to publish the data from the study reported. As the data are confidential, the content of this article has been removed from the jou...
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Chapter and Conference Paper
Solutions of Partition Function-Based TU Games for Cooperative Communication Networking
In networked communications nodes choose among available actions and benefit from exchanging information through edges, while continuous technological progress fosters system functionings that increasingly oft...
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Chapter and Conference Paper
Searching for Network Modules
When analyzing complex networks, a key target is to uncover their modular structure, which means searching for a family of node subsets spanning each an exceptionally dense subnetwork. Objective function-based...
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Article
Baseline serum levels of osteopontin predict clinical response to treatment with nivolumab in patients with non-small cell lung cancer
Treatment with nivolumab improves survival and response rate in non-small cell lung cancer (NSCLC). Nevertheless, due to its high financial cost, identifying predictors of response to treatment has become an u...
