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Open AccessDietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α
In female mammals, the cessation of ovarian functions is associated with significant metabolic alterations, weight gain, and increased susceptibility to a number of pathologies associated with ageing. The mole...
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Advances in Diagnostic Imaging
Neuroendocrine tumours are a large group of rare tumours sharing common pathological and biological characteristics.
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Open AccessPancreatic serous cystoadenoma (CSA) showing increased tracer uptake at 68-GaDOTA-peptide Positron Emission Tomography (68Ga-DOTA-peptide PET-CT): a case report
Serous cysto-adenoma (SCA) is a rare benign neoplasm of the pancreas. SCA can mimic other pancreatic lesions, such as neuroendocrine tumours. 68Gallium-DOTA-peptide Positron Emission Tomography (PET) is able t...
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Terapia radiorecettoriale dei tumori neuroendocrini
La terapia radio-recettoriale (Peptide Radio-Receptor Therapy, PRRT) nei tumori neuroendocrini (NET) è un trattamento molecolare basato sull’infusione sistemica di radiofarmaci specificamente Disegnati per legare...
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Morphometric vertebral fractures in patients with castration-resistant prostate cancer undergoing treatment with radium-223: a longitudinal study in the real-life clinical practice
Radium-223 was associated with high incidence of non-vertebral fractures in patients with castration-resistant prostate cancer (CRPC). However, it is still unclear whether radium-223 may induce skeletal fragil...
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Carcinoma differenziato della tiroide metastatico con riduzione di Tg e incremento della captazione 18F-FDG-PET: evoluzione verso la radioiodio refrattarietà?
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18F-FDG uptake of brown fat and cancer: casualty or causality?
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Molecular Guidance for Planning External Beam Radiation Therapy
The year 1895, with the discovery of X-rays, can be considered as the beginning of radiotherapy. Subsequent developments were implemented to improve the quality and precision of radiation delivery. In the last...
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Risk-related 18F-FDG PET/CT and new diagnostic strategies in patients with solitary pulmonary nodule: the ITALIAN multicenter trial
Diagnosis of solitary pulmonary nodule (SPN) is an important public health issue and 18F-FDG PET/CT has proven to be more effective than CT alone. Pre-test risk stratification and clinical presentation of SPN cou...
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Performance of FDG-PET/CT in solitary pulmonary nodule based on pre-test likelihood of malignancy: results from the ITALIAN retrospective multicenter trial
The aim of this study was to determine the performance of 18F-FDG-PET/CT in patients with solitary pulmonary nodule (SPN), stratifying the risk according to the likelihood of pulmonary malignancy.
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Radioiodine Therapy of Hyperthyroidism
Thyroid benign disorders have been successfully treated by means of administration of 131iodine since the 1940s. The efficacy and safety of this treatment and the advantages over thyroid surgery made its succe...
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Open AccessSelective proliferative response of microglia to alternative polarization signals
Microglia are resident myeloid cells of the central nervous system (CNS) that are maintained by self-renewal and actively participate in tissue homeostasis and immune defense. Under the influence of endogenous...
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Open AccessSelf-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge
Beyond the physiology of reproduction, estrogen controls the homeostasis of several tissues. Although macrophages play a key role in tissue remodeling, the interplay with estrogen is still ill defined. Using a...
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Radionuclide Imaging (SPECT)
Nuclear medicine techniques play a fundamental role in the study of neuroendocrine tumours (NET) having the capability to image in vivo the amine pathway and the overexpression of the somatostatin receptors by...
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Un caso di paraganglioma metastatico recidivo
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Riscontro di ipofisite linfocitaria in paziente con diagnosi di tubercolosi
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Open AccessHeterogeneous induction of microglia M2a phenotype by central administration of interleukin-4
Acquisition of the M1 or M2 phenotypes by microglia has been shown to occur during the development of pathological conditions, with M1 activation being widely involved in neurotoxicity in relation with the ana...
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Imaging acute spinal myelitis with 18F-FDG PET/CT
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Un caso di tumore neuroendocrino metastatico trattato con successo con terapia radio recettoriale
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Riscontro incidentale di MEN1 in paziente con dispepsia
