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  1. Article

    Open Access

    A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infection

    Approaches are needed for therapy of the severe acute respiratory syndrome from SARS-CoV-2 coronavirus (COVID-19). Interfering with the interaction of viral antigens with the angiotensin converting enzyme 2 (A...

    Ami Miller, Adam Leach, Jemima Thomas, Craig McAndrew, Emma Bentley in Scientific Reports (2021)

  2. Article

    Open Access

    Implementing a method for engineering multivalency to substantially enhance binding of clinical trial anti-SARS-CoV-2 antibodies to wildtype spike and variants of concern proteins

    Infection by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes COVID-19 disease. Therapeutic antibodies are being developed that interact with the viral spike proteins to limit viral infe...

    Adam Leach, Ami Miller, Emma Bentley, Giada Mattiuzzo, Jemima Thomas in Scientific Reports (2021)