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  1. Article

    Open Access

    Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smears

    Acute Lymphoblastic Leukaemia (ALL) is the most common cancer in children. Over the past four decades, research has advanced the treatment of this cancer from a less than 60% chance of survival to over 85% tod...

    Nicholas CL Wong, Gavin D Meredith, George Marnellos, Miroslav Dudas… in GigaScience (2015)

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    Article

    Measurement of kinase activation in single mammalian cells

    We demonstrate a new method for the simultaneous measurement of the activation of key regulatory enzymes within single cells. To illustrate the capabilities of the technique, the activation of protein kinase C...

    Gavin D. Meredith, Christopher E. Sims, Joseph S. Soughayer… in Nature Biotechnology (2000)