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    Article

    WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics

    5-HT2C agonists, by decreasing mesolimbic dopamine without affecting nigrostriatal dopamine, are predicted to have antipsychotic efficacy with low extrapyramidal side effects (EPS). Combining 5-HT2C agonists with...

    Steven M. Grauer, Radka Graf, Rachel Navarra, Amy Sung… in Psychopharmacology (2009)

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    Article

    Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents

    Activation of one or more of the serotonin (5-HT) receptors may play a role in mediating the antidepressant effects of SSRIs.

    Sharon Rosenzweig-Lipson, Annmarie Sabb, Gary Stack, Paul Mitchell… in Psychopharmacology (2007)

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    Chapter

    Leukodepletion to Prevent Transfusion Reactions: Effects on Cytokines and Other Biologic Response Modifiers

    The role of allogeneic leukocytes in causing febrile nonhemolytic trans­fusion (FNHTR) reactions has been known since the mid-1950s. Recent data suggests plausible mechanisms in which pro-inflammatory cytokine...

    Gary Stack, Edward L. Snyder in Clinical Benefits of Leukodepleted Blood Products (1995)