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  1. No Access

    Article

    WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics

    5-HT2C agonists, by decreasing mesolimbic dopamine without affecting nigrostriatal dopamine, are predicted to have antipsychotic efficacy with low extrapyramidal side effects (EPS). Combining 5-HT2C agonists with...

    Steven M. Grauer, Radka Graf, Rachel Navarra, Amy Sung… in Psychopharmacology (2009)

  2. No Access

    Article

    Activation of estrogen receptor-β regulates hippocampal synaptic plasticity and improves memory

    Estrogens have long been implicated in influencing cognitive processes, yet the molecular mechanisms underlying these effects and the roles of the estrogen receptors alpha (ERα) and beta (ERβ) remain unclear. ...

    Feng Liu, Mark Day, Luis C Muñiz, Daniel Bitran, Robert Arias… in Nature Neuroscience (2008)