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Article
Open AccessNew insecticide screening platforms indicate that Mitochondrial Complex I inhibitors are susceptible to cross-resistance by mosquito P450s that metabolise pyrethroids
Fenazaquin, pyridaben, tolfenpyrad and fenpyroximate are Complex I inhibitors offering a new mode of action for insecticidal malaria vector control. However, extended exposure to pyrethroid based products such as...
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Article
Open AccessLaboratory transmission potential of British mosquitoes for equine arboviruses
There has been no evidence of transmission of mosquito-borne arboviruses of equine or human health concern to date in the UK. However, in recent years there have been a number of outbreaks of viral diseases sp...
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Article
Open AccessImproved reference genome of Aedes aegypti informs arbovirus vector control
Female Aedes aegypti mosquitoes infect more than 400 million people each year with dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress in understanding the biology of mosquito...
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Article
Efficient ΦC31 integrase–mediated site-specific germline transformation of Anopheles gambiae
Anopholes gambiae has proven trickier to genetically manipulate than other mosquito species. Here, Pondeville et al. provide an optimized Protocol for ΦC31-mediated trangenesis that can generate transgenic A. gam...
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Article
Open AccessDemasculinization of the Anopheles gambiae X chromosome
In a number of organisms sex-biased genes are non-randomly distributed between autosomes and the shared sex chromosome X (or Z). Studies on Anopheles gambiae have produced conflicting results regarding the underr...
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Article
Open AccessAnalysis of apyrase 5' upstream region validates improved Anopheles gambiae transformation technique
Genetic transformation of the malaria mosquito Anopheles gambiae has been successfully achieved in recent years, and represents a potentially powerful tool for researchers. Tissue-, stage- and sex-specific promot...
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Article
Anti-malarial mosquitoes?
Researchers have generated genetically altered mosquitoes with a reduced ability to transmit the malaria parasite in the lab. This is an important proof of principle, but there's still a long road ahead.
