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Article
Open AccessCo-localization of clusters of TCR-regulated genes with TAD rearrangements
Gene expression has long been known to be influenced by the relative proximity of DNA regulatory elements. Topologically associating domains (TADs) are self-interacting genomic regions involved in regulating g...
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Article
Open AccessAnalysis of KIR gene variants in The Cancer Genome Atlas and UK Biobank using KIRCLE
Natural killer (NK) cells represent a critical component of the innate immune system’s response against cancer and viral infections, among other diseases. To distinguish healthy host cells from infected or tum...