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    Article

    Chromosome-length genome assemblies and cytogenomic analyses of pangolins reveal remarkable chromosome counts and plasticity

    We report the first chromosome-length genome assemblies for three species in the mammalian order Pholidota: the white-bellied, Chinese, and Sunda pangolins. Surprisingly, we observe extraordinary karyotypic pl...

    Marlys L. Houck, Klaus-Peter Koepfli, Taylor Hains, Ruqayya Khan in Chromosome Research (2023)

  2. No Access

    Chapter and Conference Paper

    t-SNE Highlights Phylogenetic and Temporal Patterns of SARS-CoV-2 Spike and Nucleocapsid Protein Evolution

    Since the beginning of the COVID-19 pandemic, whole-genome sequences of SARS-CoV-2 have been continuously added to public databases, such as NCBI Virus [4] and GISAID [3].

    Gaik Tamazian, Andrey B. Komissarov in Bioinformatics Research and Applications (2022)

  3. No Access

    Chapter and Conference Paper

    Na/K-ATPase Glutathionylation: in silico Modeling of Reaction Mechanisms

    Na,K-ATPase is a redox-sensitive transmembrane protein. Understanding the mechanisms of Na,K-ATPase redox regulation can help to prevent impairment of Na,K-ATPase functioning under pathological conditions and ...

    Yaroslav V. Solovev, Daria S. Ostroverkhova in Bioinformatics Research and Applications (2020)

  4. Article

    Open Access

    Chromosomer: a reference-based genome arrangement tool for producing draft chromosome sequences

    As the number of sequenced genomes rapidly increases, chromosome assembly is becoming an even more crucial step of any genome study. Since de novo chromosome assemblies are confounded by repeat-mediated artifacts...

    Gaik Tamazian, Pavel Dobrynin, Ksenia Krasheninnikova, Aleksey Komissarov in GigaScience (2016)

  5. Article

    Open Access

    Genomic legacy of the African cheetah, Acinonyx jubatus

    Patterns of genetic and genomic variance are informative in inferring population history for human, model species and endangered populations.

    Pavel Dobrynin, Shi** Liu, Gaik Tamazian, Zijun **ong in Genome Biology (2015)

  6. Article

    Open Access

    Annotated features of domestic cat – Felis catus genome

    Domestic cats enjoy an extensive veterinary medical surveillance which has described nearly 250 genetic diseases analogous to human disorders. Feline infectious agents offer powerful natural models of deadly h...

    Gaik Tamazian, Serguei Simonov, Pavel Dobrynin, Alexey Makunin in GigaScience (2014)