8 Result(s)
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Article
Open AccessEndothelial sensing of AHR ligands regulates intestinal homeostasis
Endothelial cells line the blood and lymphatic vasculature, and act as an essential physical barrier, control nutrient transport, facilitate tissue immunosurveillance and coordinate angiogenesis and lymphangio...
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Article
Open AccessAuthor Correction: OmpK36-mediated Carbapenem resistance attenuates ST258 Klebsiella pneumoniae in vivo
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Open AccessFlagellin outer domain dimerization modulates motility in pathogenic and soil bacteria from viscous environments
Flagellar filaments function as the propellers of the bacterial flagellum and their supercoiling is key to motility. The outer domains on the surface of the filament are non-critical for motility in many bacte...
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Article
Open AccessOmpK36-mediated Carbapenem resistance attenuates ST258 Klebsiella pneumoniae in vivo
Carbapenem-resistance in Klebsiella pneumoniae (KP) sequence type ST258 is mediated by carbapenemases (e.g. KPC-2) and loss or modification of the major non-selective porins OmpK35 and OmpK36. However, the mechan...
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Article
Open AccessAuthor Correction: Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
The original version of this Article contained an error in the spelling of the author David Ruano-Gallego, which was incorrectly given as David R. Gallego. This has now been corrected in both the PDF and HTML ...
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Article
Open AccessHost-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
Niche-adaptation of a bacterial pathogen hinges on the ability to recognize the complexity of signals from the environment and integrate that information with the regulation of genes critical for infection. He...
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Open AccessThe Hd, Hj, and Hz66 flagella variants of Salmonella enterica serovar Typhi modify host responses and cellular interactions
Salmonella Typhi, the causative agent of typhoid fever, is a monophyletic, human-restricted bacterium that exhibits limited phenotypic variation. S. Typhi from Indonesia are a notable exception, with circulating ...
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Open AccessThe Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation
The hallmark of enteropathogenic Escherichia coli (EPEC) infection is the formation of actin-rich pedestal-like structures, which are generated following phosphorylation of the bacterial effector Tir by cellular ...
