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Article
Open AccessEffect of testosterone therapy on breast tissue composition and mammographic breast density in trans masculine individuals
The effect of gender-affirming testosterone therapy (TT) on breast cancer risk is unclear. This study investigated the association between TT and breast tissue composition and breast tissue density in trans ma...
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Article
Open AccessAssociation of early menarche with breast tumor molecular features and recurrence
Early menarche is an established risk factor for breast cancer but its molecular contribution to tumor biology and prognosis remains unclear.
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Article
Associations of stem cell markers CD44, CD24 and ALDH1A1 with mammographic breast density in women with benign breast biopsies
We examined associations of CD44, CD24 and ALDH1A1 breast stem cell markers with mammographic breast density (MBD), a well-established breast cancer (BCa) risk factor.
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Article
Open AccessAssociations of alcohol consumption with breast tissue composition
We investigated the associations of alcohol with percentage of epithelium, stroma, fibroglandular tissue (epithelium + stroma), and fat in benign breast biopsy samples.
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Article
Open AccessAssociation of body mass index and inflammatory dietary pattern with breast cancer pathologic and genomic immunophenotype in the nurses’ health study
Breast tumor immune infiltration is clearly associated with improved treatment response and outcomes in breast cancer. However, modifiable patient factors associated with breast cancer immune infiltrates are p...
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The Macroscopic and Microscopic Evaluation of Breast and Axillary Lymph Node Specimens Following Neoadjuvant Systemic Therapy for Breast Cancer
The evaluation of breast and axillary lymph node specimens from patients treated with neoadjuvant systemic therapy (NAST) for breast cancer presents unique challenges in addition to those encountered during th...
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Article
Open AccessAssociations of reproductive breast cancer risk factors with breast tissue composition
We investigated the associations of reproductive factors with the percentage of epithelium, stroma, and fat tissue in benign breast biopsy samples.
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Article
Open AccessLow dose environmental radon exposure and breast tumor gene expression
The International Agency for Research on Cancer classified radon and its decay-products as Group-1-human-carcinogens, and with the current knowledge they are linked specifically to lung cancer. Biokinetic mode...
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Article
Open AccessErythrocyte membrane fatty acids and breast cancer risk by tumor tissue expression of immuno-inflammatory markers and fatty acid synthase: a nested case-control study
Previous studies of fatty acids and breast cancer risk have shown mixed results, which may be due in part to tumor heterogeneity. Prior research has also illustrated an important role of specific fatty acids i...
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Article
Open AccessPrognostic and predictive value of androgen receptor expression in postmenopausal women with estrogen receptor-positive breast cancer: results from the Breast International Group Trial 1–98
The androgen receptor (AR) is an emerging prognostic marker and therapeutic target in breast cancer. AR is expressed in 60–80% of breast cancers, with higher prevalence among estrogen receptor-positive (ER+) t...
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Open AccessAndrogen receptor expression in normal breast tissue and subsequent breast cancer risk
Sex steroid hormone signaling is critical in the development of breast cancers, although the role of the androgen receptor remains unclear. This study evaluated androgen receptor (AR) expression in normal brea...
